Results 251 to 260 of about 681,627 (391)

Considerations for the clinical use of teplizumab in stage 2 Type 1 diabetes: A Consensus Statement from the British Society of Paediatric Endocrinology and Diabetes (BSPED) and the Association of British Clinical Diabetologists (ABCD)

open access: yesDiabetic Medicine, EarlyView.
Abstract Introduction In 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) approved the use of teplizumab (a monoclonal anti‐CD3 antibody) to delay progression from Stage 2 to Stage 3 Type 1 diabetes in the UK. Methods To address the need for clear guidance on managing patients eligible for teplizumab therapy, the British Society of ...
Renuka P. Dias   +8 more
wiley   +1 more source

Prevalence and Predictors of Mother-to-Child Transmission of Human Immunodeficiency Virus (HIV) among HIV-exposed Infants. [PDF]

open access: yesInt J MCH AIDS
Ahenkan E   +12 more
europepmc   +1 more source

Clarity in Reporting Multiple Long‐Term Conditions in Research: The Need for Consistency and Consensus

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Multiple long‐term conditions (MLTC), also known as multimorbidity, affects a substantial proportion of the global population and represents an increasing challenge to healthcare systems, individuals and society. Despite increasing attention and investment, progress in MLTC research is hindered by conceptual inconsistencies and a lack of ...
Mark P. Funnell   +5 more
wiley   +1 more source

Long-Term Outcomes of Young Adults With Perinatal Human Immunodeficiency Virus (HIV) Infection in the United States and Puerto Rico. [PDF]

open access: yesOpen Forum Infect Dis
Kern L   +6 more
europepmc   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Testing for human immunodeficiency virus (HIV) in the eye clinic

open access: green, 2018
Morgan E. Wallace   +4 more
openalex   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

open access: yesThe FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto   +9 more
wiley   +1 more source

Hemophilia Severity and Its Association With Mental Health and Health‐Related Quality of Life—Results From a Cross‐Sectional Multicenter Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Background Limited existing research on mental health and health‐related quality of life (HRQoL) in people with hemophilia (PwH) suggests these patients still may have poor mental health despite treatment advances significantly improving somatic outcomes.
Francesca Schmitt   +16 more
wiley   +1 more source

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