Results 71 to 80 of about 2,788,771 (256)

Determinants of change in the duration of ice phenomena on the Vistula River in Toruń

Journal of Hydrology and Hydromechanics, 2015
Winter season temperatures are becoming warmer. However, the transformation of the ice regime on the Vistula River in Toruń has also been affected by river engineering.
Pawłowski Bogusław
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Potential of Manor Gardens for Natural Habitats Conservation

Journal of Landscape Ecology, 2019
Historical gardens established around manors form an integral part of the European cultural landscape. Recent studies have revealed that manor gardens may serve as local hotspots of biodiversity and provide cultural ecosystem services within urban areas ...
Šantrůčková Markéta, Demková Katarína, Dostálek Jiří, Frantík Tomáš   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Indices of human impacts on landscapes: How do they reflect the proportions of natural habitats?

Open Life Sciences
Human activities significantly influence landscapes, altering natural habitats and ecosystem services. This study examines the relationship between human impacts, measured by the hemeroby index and coefficient of anthropogenic impact (CAI´), and the ...
Šantrůčková Markéta, Demková Katarína, Frantík Tomáš, Dostálek Jiří   +3 more
doaj   +1 more source

Human Impacts on Atmospheric Chemistry

Annual Review of Earth and Planetary Sciences, 2001
An overview is given of the main anthropogenic influences on the chemistry of the atmosphere. Industrial and agricultural activities have altered the chemical composition of the atmosphere in many important ways, which is reflected especially in the distribution and concentrations of ozone in the troposphere and stratosphere.
Crutzen, P.J., Lelieveld, J.
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Land use in the tropical karst - the case of Peruaçu, Januària and Jaiba; SE Brazil. [PDF]

International Journal of Speleology, 1999
The karstic regions of the municipalities of Peruaçu, Januària and Jaiba present a variety of soil uses which are a function of the organization of the karstic relief.
Kohler Heinz Charles, dos Anjos Ferreira Pinto Sergio, de Abreu Joao Francisco   +2 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source