Results 11 to 20 of about 2,769,848 (257)

Adverse outcome pathways – development and potential regulatory application

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2021
Introduction: Over the last two decades, chemical safety assessment and regulatory toxicology have progressed from empirical science based on direct observation of apical adverse outcomes in whole organisms to a predictive practice that infers outcomes ...
Thania Rios Rossi Lima, Nathália Pereira de Souza, Lílian Cristina Pereira, João Lauro Viana de Camargo   +3 more
doaj  

The Human Impact

The American Biology Teacher, 2018
Earth in Human Hands: Shaping Our Planet's Future . By David Grinspoon. 2016. Grand Central Publishing. (ISBN 9781455589128). 522 pages. Hardcover. $28.00. Dr. Grinspoon's massive review of Earth's past, present, and future begins with a nod to the Anthropocene and the idea that humans, with regard to the state of the planet, are “at the controls ...
openaire   +2 more sources

The Impact of Social Media Usage on Human societies

Akofena
: Social media has gained significant importance in the intellectual arena, coinciding with the technological and digital revolution witnessed by the contemporary world.
The Impact of Social Media Usage on Human societies
doaj   +1 more source

Paraquat and Parkinson’s disease: a systematic review protocol according to the OHAT approach for hazard identification

Systematic Reviews, 2017
Background Parkinson’s disease (PD) is a progressive neurodegenerative condition that has genetic susceptibility, aging, and exposure to certain chemicals as risk factors.
Carolina Vaccari, Regina El Dib, João Lauro V. de Camargo   +2 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Contextual factors influencing the integration of physical activity policy, systems, and environmental interventions in the cooperative extension system: a systematic review

International Journal of Behavioral Nutrition and Physical Activity
Background Physical activity policy, systems, and environmental changes (PSEs) are effective but complex public health interventions. PSEs are increasingly being implemented through Cooperative Extension, a national system historically focused on ...
Shelly Palmer, Emily Shaw, Michelle Grocke-Dewey, Kelsay Corlew, Laura Flournoy, Laura E. Balis   +5 more
doaj   +1 more source

A spatio-temporal systematic evidence map of exposure to bisphenols and their alternatives: Social and environmental justice

Environment International
Background: Bisphenol A (BPA) and a growing number of its structural analogues and functional alternatives are widely used in consumer plastic products and therefore have high exposure potential.
Bhedita J. Seewoo, Aleksandra Gozt, Ahmed Elagali, Aoife Lyons, Henoch Kabeya, Christos Symeonides, Sarah A. Dunlop   +6 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Improvement in quality of life and loneliness after the community connections program: a community-based pilot intervention in South Australia

BMC Psychology
Background Reducing loneliness and enhancing quality of life (QoL) are key public health priorities. However, limited empirical research examines the impact of community-based interventions on both loneliness and QoL.
Bryony Jardine, Pei Jie Tan, Ashleigh Powell, Diana Eyers-White, Catherine Mackenzie, Ian Goodwin-Smith, Sandra Robinson, Penny Baldock, Mia Zaccardo, Celina Valente, Camilla Trenerry, Svetlana Bogomolova   +11 more
doaj   +1 more source