Results 71 to 80 of about 17,376,473 (292)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Terrestrial isopod (Crustacea, Isopoda) assemblages near a local road in a forested region from Oaș Mountains, North-Western Romania

open access: yesStudia Universitatis Babeș-Bolyai. Biologia
Roads are in permanent expansion at the global level and have numerous negative effects, impacting even the litter-dwelling invertebrates from their vicinity.
Sára FERENȚI   +4 more
doaj   +1 more source

The ‘Human Rights Component’ of Foreign Policy

open access: yes, 2022
Framed into the broader conceptual debate that addresses the controversial role of human rights in the foreign policies of states, this book aims to critically investigate whether, how and to what extent human rights matter in the definition of Italy’s ...
de Perini, Pietro
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Evaluating Student Impact Capacity: A Guidebook for Teachers

open access: yes
This guidebook is designed to assist course coordinators in evaluating students’ impact capacity in their courses. It contains the definition of students’ impact capacity and a non-exhaustive list of example questions for evaluating societal impact ...
Evaluating Societal Impact
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Antropojenik Jeomorfoloji Yaklaşımı İle Topografyadaki İnsan Etkisinin Modellenmesi: Muğla İlinin Kuzeybatı Sahası Örneği

open access: yesDünya Coğrafyası ve Kalkınma Perspektifi Dergisi
İnsan faaliyetlerinin doğal koşullardaki baskı ve etki boyutlarının artması, jeomorfolojik unsurlarda da değişimlere yol açmaktadır. Bu çalışmada Muğla ilinin kuzey ve batısındaki 6 ilçe kapsamında zamansal ve mekânsal açıdan farklı kriterler ...
Selin Apatarkan   +2 more
doaj   +1 more source

Impact Indicators: Overview and Menu Selection

open access: yes
The tool Impact indicators - overview and selection menu was designed by the Evaluating Societal Impact (ESI) strategic project at Erasmus University Rotterdam for academics and research units who want to indicate how their academic work relates to ...
Evaluating Societal Impact
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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