Results 71 to 80 of about 17,376,473 (292)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Roads are in permanent expansion at the global level and have numerous negative effects, impacting even the litter-dwelling invertebrates from their vicinity.
Sára FERENȚI +4 more
doaj +1 more source
The ‘Human Rights Component’ of Foreign Policy
Framed into the broader conceptual debate that addresses the controversial role of human rights in the foreign policies of states, this book aims to critically investigate whether, how and to what extent human rights matter in the definition of Italy’s ...
de Perini, Pietro
core +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Evaluating Student Impact Capacity: A Guidebook for Teachers
This guidebook is designed to assist course coordinators in evaluating students’ impact capacity in their courses. It contains the definition of students’ impact capacity and a non-exhaustive list of example questions for evaluating societal impact ...
Evaluating Societal Impact
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
İnsan faaliyetlerinin doğal koşullardaki baskı ve etki boyutlarının artması, jeomorfolojik unsurlarda da değişimlere yol açmaktadır. Bu çalışmada Muğla ilinin kuzey ve batısındaki 6 ilçe kapsamında zamansal ve mekânsal açıdan farklı kriterler ...
Selin Apatarkan +2 more
doaj +1 more source
Impact Indicators: Overview and Menu Selection
The tool Impact indicators - overview and selection menu was designed by the Evaluating Societal Impact (ESI) strategic project at Erasmus University Rotterdam for academics and research units who want to indicate how their academic work relates to ...
Evaluating Societal Impact
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

