Results 121 to 130 of about 2,872,047 (257)

The human impact of commercial delivery cycling injuries: a pilot retrospective cohort study. [PDF]

Pilot Feasibility Stud, 2022
Sarkies MN, Hemmert C, Pang YC, Shiner CT, McDonell K, Mitchell R, Lystad RP, Novy M, Christie LJ.   +8 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Human impact on the recent population history of the elusive European wildcat inferred from whole genome data. [PDF]

BMC Genomics, 2022
Nieto-Blázquez ME, Schreiber D, Mueller SA, Koch K, Nowak C, Pfenninger M.   +5 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Community Essay: Sustainability science – and what’s needed beyond science

Sustainability: Science, Practice, & Policy, 2005
Educating broadly about the science and technologies of sustainability is essential, because it convinces us that a successfully sustainable future is being undermined.
Paul H. Reitan
doaj  

The Human Impact on All Soil-Forming Factors during the Anthropocene. [PDF]

ACS Environ Au, 2022
Dror I, Yaron B, Berkowitz B.
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Ancient environmental DNA indicates limited human impact on marine biodiversity in pre-industrial Iceland. [PDF]

Philos Trans R Soc Lond B Biol Sci
Holman LE, Arfaoui EMR, Pedersen LB, Farnsworth WR, Ascough P, Butler P, Guðmundsdóttir ER, Reynolds DJ, Trofimova T, Wilkin JTR, Carøe C, Frøslev TG, Harrison R, Gopalakrishnan S, Pedersen MW, Scourse J, Bohmann K.   +16 more
europepmc   +2 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source