Results 21 to 30 of about 2,769,848 (257)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Looking at the big picture: demonstrating benefits of Bayesian latent cluster spatio-temporal analysis for understanding maternal prescription opioids misuse

BMC Public Health
Background As the opioid crisis rages, maternal prescription opioid misuse (MPOM) is particularly concerning because it influences both the mother and child’s wellbeing. However, little was known about the trend of MPOM and its county-level risk factors.
Xueyi Xing, D. Max Crowley, Christian M. Connell   +2 more
doaj   +1 more source

Multiparameter analysis of Diuron and its metabolites (DCA and DCPMU) in different stages of zebrafish (Danio rerio) development

Frontiers in Water
IntroductionDiuron (3-(3,4-dichlorophenyl)-1,1-dimethylurea) is a prominent herbicide in Brazilian agriculture, particularly in sugarcane farming. This herbicide persists in the environment and is transformed into potentially toxic metabolites, such as 3,
Paloma Vitória Lima Peixoto, Bianca Camargo Penteado Sales, Luiza Aggio, Cristina Viriato, Lilian Cristina Pereira   +4 more
doaj   +1 more source

Subfossil Cladocera as a powerful tool for paleoecological reconstruction

Advances in Oceanography and Limnology, 2016
Subfossil Cladocera (Crustacea, Branchiopoda) represent one of the most valuable biological proxies preserved in lake sediments that can be studied for reconstruction purposes.
Monica Tolotti, Manuela Milan, Krystyna Szeroczyńska   +2 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

BMI or not to BMI? debating the value of body mass index as a measure of health in adults

International Journal of Behavioral Nutrition and Physical Activity
Body mass index (BMI) is used across public health to calculate height to weight ratio and translate into weight status. Whether BMI is appropriate as an individual- or population-level health measure for adults is debated.
Carmen Byker Shanks, Meg Bruening, Amy L. Yaroch   +2 more
doaj   +1 more source

The power of lived experience in optimizing US policymakers’ engagement with substance use research: A series of rapid-cycle randomized controlled trials

Drug and Alcohol Dependence Reports
Background: Research can inform policies on substance use/substance use disorders (SU/SUDs), yet there is limited experimental investigation into strategies for optimizing policymakers’ engagement with SU/SUD research.
Elizabeth C. Long, Riley Loria, Jessica Pugel, Patrick O’Neill, Camille C. Cioffi, Charleen Hsuan, Glenn Sterner, D. Max Crowley, J. Taylor Scott   +8 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Ecogeomorphology and vulnerability in a Mediterranean ria-type coast (La Maddalena Archipelago, NE Sardinia, western Mediterranean)

Journal of Maps, 2021
This paper presents a map describing the main geomorphological and sedimentological features, hydrodynamics, benthic habitat distributions and human impact on the coastal and marine areas of the Archipelago of La Maddalena (NE Sardinia, western ...
Sandro De Muro, Carla Buosi, Manuela Biondo, Angelo Ibba, Andrea Ruju, Daniele Trogu, Marco Porta   +6 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source