Results 201 to 210 of about 2,788,771 (256)
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
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2021
Coastal soft sediments are closely linked to human activity both on the land and at sea and consequently they are subjected to a wide array of human impacts. Looking for some general patterns in the consequences of impacts, this chapter identifies a range of different ecological changes as a result of direct impacts and then moves to address indirect ...
Simon F. Thrush +3 more
openaire +1 more source
Coastal soft sediments are closely linked to human activity both on the land and at sea and consequently they are subjected to a wide array of human impacts. Looking for some general patterns in the consequences of impacts, this chapter identifies a range of different ecological changes as a result of direct impacts and then moves to address indirect ...
Simon F. Thrush +3 more
openaire +1 more source
Science
Behind the myriad upheavals U.S. science has faced during the first 100 days of President Donald Trump’s administration, countless researchers are fighting for their careers and aspirations.
Sara, Reardon +3 more
openaire +2 more sources
Behind the myriad upheavals U.S. science has faced during the first 100 days of President Donald Trump’s administration, countless researchers are fighting for their careers and aspirations.
Sara, Reardon +3 more
openaire +2 more sources
1992
Abstract Environmental change spans all of human time. Even so-called primitive peoples have left their mark on the earth. Fire, the oldest of anthropogenic landscape modifiers, has long been implicated in the origins and maintenance of tropical savannahs and mid-latitude grasslands, and biggame hunters of the Stone Age may have caused ...
S Robert Aiken, Colin H Leigh
openaire +1 more source
Abstract Environmental change spans all of human time. Even so-called primitive peoples have left their mark on the earth. Fire, the oldest of anthropogenic landscape modifiers, has long been implicated in the origins and maintenance of tropical savannahs and mid-latitude grasslands, and biggame hunters of the Stone Age may have caused ...
S Robert Aiken, Colin H Leigh
openaire +1 more source
Telepresence Robots and Their Impact on Human-Human Interaction
2020In an increasingly globalized world remote communication becomes ever more crucial. Hence, telepresence robots gain importance as they simplify attending important but distant events. However, research regarding human affinity towards a person by interacting directly or through a telepresence robot with another individual has not been undertaken ...
Lisa Keller +3 more
openaire +2 more sources
1985
The fundamental role of climate for the fate of mankind is increasingly being recognized at both the international and national levels (World Meteorological Organization, 1980, pp. 7–10, 28–37; World Meteorological Organization-ICSU, 1975, pp. 1–3; United Nations Environment Programme, 1979, pp. 1–16; National Climate Program Office NOAA, 1980, pp. 1–4,
openaire +1 more source
The fundamental role of climate for the fate of mankind is increasingly being recognized at both the international and national levels (World Meteorological Organization, 1980, pp. 7–10, 28–37; World Meteorological Organization-ICSU, 1975, pp. 1–3; United Nations Environment Programme, 1979, pp. 1–16; National Climate Program Office NOAA, 1980, pp. 1–4,
openaire +1 more source