Results 61 to 70 of about 2,872,047 (257)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Trust and overreliance on ChatGPT and its implications on critical thinking: an exploration in health policy

Discover Public Health
International organizations have provided guidelines for the use of AI, encouraging its responsible development and promoting human-centered, trust-based use.
Carlos Alberto Rosas-Jiménez, Cynthia Lokker, Bonny Ibhawoh, Lisa Schwartz   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Feasibility study of a screening decision tool for allocating adults into food is medicine programs as an effective approach to target clinical and dietary outcomes among rural and urban adults

Frontiers in Public Health
ObjectiveEvaluate feasibility (primary), clinical, and cost outcomes (secondary) associated with the use of a screening decision tool for allocating rural and urban adults with hypertension into in a food is medicine (FIM) program.DesignParticipants were
Alison Gustafson, Carolyn Lauckner, Joshua L. Bush, Emily Dimond, Carolina Morales Serrano, Christa Mayfield, Elizabeth T. Anderson Steeves   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Advancing implementation science in community settings: the implementation strategies applied in communities (ISAC) compilation

International Journal of Behavioral Nutrition and Physical Activity
Background Implementation strategies have predominantly been operationalized and studied in clinical settings. Implementation strategies are also needed to improve evidence-based intervention (EBI) integration in community settings, but there is a lack ...
Laura E. Balis, Bailey Houghtaling, Whitney Clausen, Hannah Lane, Marilyn E. Wende, Emiliane Pereira, Gabriella M. McLoughlin, Samantha M. Harden   +7 more
doaj   +1 more source

THE PALYNOLOGY CONTRIBUTION IN PALAEOENVIRONMENT INVESTIGATION. A CASE-STUDY OF A LATEGLACIAL-HOLOCENE SEDIMENTARY SEQUENCE NEAR BOLOGNA (NORTHERN ITALY)

EQA, 2017
The palynological studies are extremely relevant in the investigation of the evolution of palaeoenvironments. A case of pedopalynological studies was applied to the Lateglacial to Holocene sedimentary sequence derived from a small site located in San ...
Marco Marchesini, Silvia Marvelli, Antonella Lobietti   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Human Impacts on Holocene Vegetation and Wetland Degradation in the Lower Pearl River, Southern China

Land
Reconstructing Holocene vegetation history and human impact on vegetation is critical for understanding past interactions between humans and nature.
Yaze Zhang, Yanwei Zheng, Qinghua Gong, Shuqing Fu, Cong Chen, Yongjie Tang, Xiao Zhang, Qiuchi Wan, Kangyou Huang, Zhuo Zheng   +9 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source