Results 41 to 50 of about 2,788,771 (256)
Revue de Primatologie, 2014 Chimpanzees and humans have co-existed in Africa for millennia. The forests inhabited by chimpanzees have experienced numerous changes in recent time, most notably during the last 12,000 years, as the current interglacial age started.
Thibaud Gruber
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Historical Introduction of Japanese Wild Mice, Mus musculus, from South China and the Korean Peninsula [PDF]
Animal Systematics, Evolution and Diversity, 2013 In Japan, the wild house mouse Mus musculus consists of two lineages, one from Southeast Asia (Mus musculus castaneus; CAS) and one from northern Eurasia (Mus musculus musculus; MUS). However, the exact origins of the parental lineages are unclear.
Mitsuo Nunome +2 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Embryotoxicity Induced by Triclopyr in Zebrafish (Danio rerio) Early Life Stage
ToxicsTriclopyr, an auxin-like herbicide that is widely employed for managing weeds in food crops and pastures, has been identified in various environmental settings, particularly aquatic ecosystems.
Ítalo Bertoni +4 more
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Ribogospodarsʹka Nauka Ukraïni, 2019 Purpose. To establish the nature of changes in physiological and biochemical parameters of fish, the qualitative and quantitative composition of their parasitocenoses, depending on the degree of the pollution of water bodies. Methodology.
Ju. Kovalenko +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Frontiers in Microbiology, 2019 Archaea play vital roles in global biogeochemical cycles, particularly in nitrification and methanogenesis. The recovery of archaeal community following disturbance is essential for maintaining the stability of ecosystem function.
Yu Wang +7 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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