Results 101 to 110 of about 17,376,473 (292)
The future of human rights impact assessments of trade agreements [PDF]
, 2009 The Future of Human Rights Impact Assessments of Trade Agreements develops a methodology for human rights impact assessments of trade agreements and considers whether there is any value in using the methodology on a sustained basis to ensure that the ...
Studie- en Informatiecentrum Mensenrecht +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
CGIAR GENDER Impact Platform Newsletter, November-December 2022, issue 3
, 2023 In this issue, we share with you latest news from the CGIAR GENDER Impact Platform as well as updates on gender research from across CGIAR's research portfolio.
CGIAR GENDER Impact Platform
core +1 more source
Biological Activity of Mountain Soils of the Western Caucasus after Deforestation
Лесной журналA study of a set of indicators characterizing the ecological state of forest soils in the mountains of the North-Western Caucasus under broad-leaved and mixed forests has been conducted.
Aslan K. Shkhapatsev +5 more
doaj +1 more source
Knowledge and Management of Aquatic Ecosystems, 2018 We studied the variability of physico-chemical parameters in water, and heavy metal contents in water and sediment over time and along the Carpathian Biała Tarnowska River (southern Poland) and related them to catchment geology, human impact and the ...
Szarek-Gwiazda Ewa +3 more
doaj +1 more source
Flows of Knowledge: A Method for Impact Assessment
The Flows of Knowledge evaluation method, as introduced by Meagher, Lyall and Nutley (2008) and described in Edwards and Meagher (2020), provides a framework for assessing the impacts of scientific research on policy and practice.
Evaluating Societal Impact
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Preparing case studies for impact within SEP (2021-2027)
Every six years, on a rolling basis, Dutch universities and research institutes are evaluated according to the Strategy Evaluation Protocol (SEP).Based on the experiences with the Strategy Evaluation Protocol (SEP) at the Erasmus University Rotterdam as ...
Evaluating Societal Impact
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source