Results 81 to 90 of about 18,071,962 (296)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Proximity Lens on Structural Collaborations: A Method for Impact Assessment
This resource provides a description of ‘proximities’ in impact assessment, building on Boschma (2005) and Knoben & Oerlemans (2006). Proximity dimensions provide a lens to identify and highlight the conditions that enable successful cooperation and ...
Evaluating Societal Impact
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FROM RESEARCH TO IMPACT: Towards just and resilient agri-food systems [PDF]
, 2023 The international research conference “From research to impact: Towards just and resilient agri-food systems” will address the gender and social inequalities that lie at the heart of food systems.
CGIAR GENDER Impact Platform
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Impact Strategy Development: Questions Bank and Interview Guide
The tool ‘Impact Strategy Development: Questions Bank and Interview Guide’ consists of (1) a three step interview guide and (2) an Excel file with a questions bank to use and tailor for your interviews or other methods for engaging with your community ...
Evaluating Societal Impact
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Rewiring the Evaluation Marketplace for a Changing World
Journal of MultiDisciplinary EvaluationThis issue of JMDE asks how evaluation should respond to the transformational imperative to contribute to the radical changes essential for a regenerative, socially just, and equitable future for humanity and the planet.
Nancy MacPherson +2 more
doaj
Miscellanea Geographica: Regional Studies on DevelopmentThis study investigates the impact of river engineering on the morphometry of the Vistula River channel near Warsaw, Poland, over a 172-year period. This research focuses on the examination of modifications in the Vistula channel between 1843 and 2015 ...
Poławska Martyna, Giriat Dorota
doaj +1 more source
Determinants of change in the duration of ice phenomena on the Vistula River in Toruń
Journal of Hydrology and Hydromechanics, 2015 Winter season temperatures are becoming warmer. However, the transformation of the ice regime on the Vistula River in Toruń has also been affected by river engineering.
Pawłowski Bogusław
doaj +1 more source
Impact Indicators: Overview and Menu Selection
The tool Impact indicators - overview and selection menu was designed by the Evaluating Societal Impact (ESI) strategic project at Erasmus University Rotterdam for academics and research units who want to indicate how their academic work relates to ...
Evaluating Societal Impact
core +1 more source