Results 51 to 60 of about 17,376,473 (292)

Impact Activities Catalogue

TThis tool presents a selection of competences that are relevant for societal impact. The content is presented as a non-exhaustive list of competences that academics can develop for impact-oriented academic activities. Alongside each competence and its
Evaluating Societal Impact
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Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Embryotoxicity Induced by Triclopyr in Zebrafish (Danio rerio) Early Life Stage

Toxics
Triclopyr, an auxin-like herbicide that is widely employed for managing weeds in food crops and pastures, has been identified in various environmental settings, particularly aquatic ecosystems.
Ítalo Bertoni, Bianca Camargo Penteado Sales, Cristina Viriato, Paloma Vitória Lima Peixoto, Lílian Cristina Pereira   +4 more
doaj   +1 more source

Effect of antropogenic pollution on physiological and biochemical parameters of fish and composition of their parasitocenoses

Ribogospodarsʹka Nauka Ukraïni, 2019
Purpose. To establish the nature of changes in physiological and biochemical parameters of fish, the qualitative and quantitative composition of their parasitocenoses, depending on the degree of the pollution of water bodies. Methodology.
Ju. Kovalenko, O. Shlapak, A. Potrokhov, O. Zin'kovskiy   +3 more
doaj   +1 more source

Experience and lessons from health impact assessment for human rights impact assessment [PDF]

, 2015
As globalisation has opened remote parts of the world to foreign investment, global leaders at the United Nations and beyond have called on multinational companies to foresee and mitigate negative impacts on the communities surrounding their overseas ...
Wielga, Mark, Mitchell G. Weiss, Mirko S. Winkler, Utzinger, Jürg, Singer, Burton H., Winkler, Mirko S., Weiss, Mitchell G., Mark Wielga, Burton H. Singer, Salcito, Kendyl, Gary R. Krieger, Krieger, Gary R., Jürg Utzinger, Kendyl Salcito   +13 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Anthropogenic Pollution Intervenes the Recovery Processes of Soil Archaeal Community Composition and Diversity From Flooding

Frontiers in Microbiology, 2019
Archaea play vital roles in global biogeochemical cycles, particularly in nitrification and methanogenesis. The recovery of archaeal community following disturbance is essential for maintaining the stability of ecosystem function.
Yu Wang, Yiguo Hong, Maohua Ma, Shengjun Wu, Huub J. M. Op den Camp, Guibing Zhu, Wei Zhang, Fei Ye   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Impact Strategy Development Toolkit

This tool outlines the process and useful tools for developing school-level impact strategies. It guides you through the strategy development journey, from the initial preparatory activities to the evaluation.
Evaluating Societal Impact
core   +1 more source