Results 71 to 80 of about 5,898,168 (296)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The Effects of Age and Gender on Adolescent Mental Health Stigma. An International Study in the Iberian Peninsula

open access: yesClínica y Salud. Investigación Empírica en Psicología
Background: Mental health stigma is a phenomenon present in adolescents. Age or gender are important variables to provide further intervention on stigma in this population.
Clara González-Sanguino   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Can humanoid robots be used as a cognitive offloading tool?

open access: yesCognitive Research
Cognitive load occurs when the demands of a task surpass the available processing capacity, straining mental resources and potentially impairing performance efficiency, such as increasing the number of errors in a task.
Shari Cavicchi   +4 more
doaj   +1 more source

Toward Competent Robot Apprentices: Enabling Proactive Troubleshooting in Collaborative Robots

open access: yesMachines
For robots to become effective apprentices and collaborators, they must exhibit some level of autonomy, for example, recognizing failures and identifying ways to address them with the aid of their human teammates.
Christopher Thierauf   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Enhancing theory of mind in autism through humanoid robot interaction in a randomized controlled trial

open access: yesScientific Reports
Autism Spectrum Disorder presents significant challenges in social cognition, particularly in understanding others’ thoughts, emotions, and intentions. Traditional interventions often rely on role-playing games with human therapists or inanimate objects,
Davide Ghiglino   +6 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Improving Sensor Interoperability between Contactless and Contact-Based Fingerprints Using Pose Correction and Unwarping

open access: yesIET Biometrics, 2023
Current fingerprint identification systems face significant challenges in achieving interoperability between contact-based and contactless fingerprint sensors.
Laurenz Ruzicka   +5 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

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