Results 81 to 90 of about 5,898,168 (296)
Scientific ReportsAs robots are becoming collaborators in various domains, understanding if humans perceive them as moral and intentional agents is pivotal. This study investigated the malleability of human attributions of value alignment and intentionality to a humanoid ...
Serena Marchesi +3 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
ChildrenBackground/objectives: This study examined the association between maternal anger, children’s externalizing symptoms, and the moderating impact of maternal adverse childhood experiences (ACEs) in the context of intimate partner violence (IPV).
Tiago Castro +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Knowledge Encoding in Game Mechanics: Transfer-Oriented Knowledge Learning in Desktop-3D and VR
International Journal of Computer Games Technology, 2019 Affine Transformations (ATs) are a complex and abstract learning content. Encoding the AT knowledge in Game Mechanics (GMs) achieves a repetitive knowledge application and audiovisual demonstration.
Sebastian Oberdörfer +1 more
doaj +1 more source
Towards Simulating Humans in Augmented Multi-party Interaction [PDF]
, 2005 Human-computer interaction requires modeling of the user. A user profile typically contains preferences, interests, characteristics, and interaction behavior.
Nijholt, Anton
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Environment, Human, Problems, Needs & Information! How dose arrange this puzzle? What is the information gathering (IG)? [PDF]
, 2007 The environment is a field that interaction between world elements was occurred on it. The environment produces some information, and affects other elements that exist on that field. This interaction can be defined as processes.
Farhadpoor, Mohammadreza
core