Results 91 to 100 of about 93,317 (199)
STAR Protocols, 2023 Summary: Transcytosis is the primary mechanism by which macro-molecules transverse epithelial cell barriers. Here, we present an assay for measuring transcytosis and recycling of IgG in intestinal epithelial Caco-2 cells and primary human intestinal ...
Keiko Maeda +4 more
doaj +1 more source
Advanced Materials Technologies, Volume 11, Issue 1, 8 January 2026.The modular, versatile, and standardized cartridge‐based culture module allows to replicate gut and vascular barriers. Its conventional handling requirements facilitate adoption by non‐technical users, while the design allows safe manipulation and retrieval of samples for permeability assays and endpoint analysis.
Lorenzo Pietro Coppadoro +6 more
wiley +1 more source
A microfluidic chip based model for the study of full thickness human intestinal tissue using dual flow [PDF]
, 2016 © 2016 Author(s). The study of inflammatory bowel disease, including Ulcerative Colitis and Crohn's Disease, has relied largely upon the use of animal or cell culture models; neither of which can represent all aspects of the human pathophysiology ...
A. Dawson +11 more
core +1 more source
Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Jialu Zhang +7 more
wiley +1 more source
The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. [PDF]
, 2018 Guanylate cyclase C (GUCY2C) is a transmembrane receptor expressed on the luminal aspect of the intestinal epithelium. Its ligands include bacterial heat-stable enterotoxins responsible for traveler\u27s diarrhea, the endogenous peptide hormones ...
Rappaport, Jeffrey A., Waldman, Scott A.
core +2 more sources
Immune and Immune‐Integrated Organoids as NextGeneration Platforms for Disease Modeling
MedComm, Volume 6, Issue 12, December 2025.This graphical abstract outlines the sources and methods for integrating immune cells into organoids. Immune cells can be derived from peripheral blood, tissues, or differentiated from human‐induced pluripotent stem cells. The immune cells are incorporated into the organoid by using coculture techniques, direct injection, as well as scaffolds and air ...
Kimiya Rashidan +5 more
wiley +1 more source
2650. Evaluating Antiviral Agents for Human Noroviruses Using a Human Intestinal Enteroid Model [PDF]
Open Forum Infectious Diseases, 2019 Abstract Background Norovirus can cause chronic infections with serious morbidity and mortality in immunocompromised patients. While there are no FDA-approved medications for these infections, nitazoxanide, ribavirin, and enterally administered pooled immunoglobulin (IVIG) are used off-label on the ...
Cortes-Penfield, Nicolas W +5 more
openaire +1 more source
Organoids, organs-on-chips and other systems, and microbiota [PDF]
, 2017 The human gut microbiome is considered an organ in its entirety and has been the subject of extensive research due to its role in physiology, metabolism, digestion, and immune regulation.
Evans, Samantha +2 more
core +2 more sources
Generation of Intestinal and Colonic Organoids Derived From Human Pluripotent Stem Cells
Biology of the Cell, Volume 117, Issue 12, December 2025.Human pluripotent stem cells can be guided through a stepwise differentiation process to produce self‐organizing intestinal and colonic organoids. The resulting organoids recapitulate fetal‐stage epithelial and mesenchymal organization, offering a powerful model to explore human gastrointestinal development and its disorders.
Lola Bonneau +7 more
wiley +1 more source
Tissue engineering laboratory models of the small intestine. [PDF]
, 2018 In recent years, three-dimensional (3D) cell culture models of the small intestine have gained much attention. These models support cell proliferation, migration, and differentiation, and encourage tissue organization which is not possible in two ...
Dosh, Rasha +3 more
core +1 more source