Results 171 to 180 of about 93,317 (199)

Human intestinal enteroids: Nonclinical applications for predicting oral drug disposition, toxicity, and efficacy.

Pharmacology & Therapeutics
The application of human enteroid systems presents a significant opportunity within the drug development pipeline, highlighting considerable potential for advancements in the characterization and evaluation of new molecular entities. Derived from LGR5+ crypt-based columnar cells, enteroid systems more accurately recapitulate the microanatomy and ...
Eimear T. O’Mahony, Christopher M. Arian, Kayenat S. Aryeh, Kai Wang, Kenneth E. Thummel, Edward J Kelly   +5 more
semanticscholar   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Co-culturing Human Intestinal Enteroid Monolayers with Innate Immune Cells

2023
The coordinated interaction between the intestinal epithelium and immune cells is required to maintain proper barrier function and mucosal host defenses to the harsh external environment of the gut lumen. Complementary to in vivo models, there is a need for practical and reproducible in vitro models that employ primary human cells to confirm and ...
Janet F, Staab, Jose M, Lemme-Dumit, Rachel, Latanich, Marcela F, Pasetti, Nicholas C, Zachos   +4 more
openaire   +2 more sources

Human intestinal enteroids for evaluating the persistence of infectious human norovirus in raw surface freshwater.

Science of The Total Environment
Globally, human norovirus (HuNoV) is the leading cause of foodborne illnesses. Norovirus transmission to fresh produce can occur via several sources, including contaminated irrigation water. HuNoV RNA has been detected in freshwater resources, but knowledge about virus infectivity is limited due to a historical lack of a HuNoV cell culture.
M. Esseili, Revati Narwankar, Riya Hooda, V. Costantini, M. K. Estes, Jan Vinjé, I. Kassem   +6 more
semanticscholar   +3 more sources

Pioneering use of human intestinal enteroids to prevent foodborne transmission of human norovirus

Trends in Food Science & Technology
This work was supported by the PID 2019-105509RJ-I00 and PID 2023-149211OB-C32 projects funded by MICIU/AEI/10.13039/501100011033 and ERDF/EU. The Accreditation as Center of Excellence Severo Ochoa CEX 2021-001189-S funded by MCIU/AEI/10.13039/501100011033 is also fully acknowledged.
W. Randazzo
semanticscholar   +3 more sources

Cervical cancer prevention and control in women living with human immunodeficiency virus

Ca-A Cancer Journal for Clinicians, 2021
Philip E Castle, Vikrant V Sahasrabuddhe
exaly  

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

Human papillomavirus vaccination 2020 guideline update: American Cancer Society guideline adaptation

Ca-A Cancer Journal for Clinicians, 2020
Robert A Smith
exaly  

Radiation therapy‐associated toxicity: Etiology, management, and prevention

Ca-A Cancer Journal for Clinicians, 2021
Kyle Wang
exaly