Results 21 to 30 of about 180,133 (201)
Water ResearchFecal-orally transmitted gastroenteritis viruses, particularly human noroviruses (HuNoVs), are a public health concern. Viral transmission risk through contaminated water results underexplored as they have remained largely unculturable until recently and the robust measuring of gastroenteritis viruses infectivity in a single cell line is challenging ...
Noelia Carmona‐Vicente +9 more
semanticscholar +8 more sources
Pioneering use of human intestinal enteroids to prevent foodborne transmission of human norovirus
Trends in Food Science & TechnologyThis work was supported by the PID 2019-105509RJ-I00 and PID 2023-149211OB-C32 projects funded by MICIU/AEI/10.13039/501100011033 and ERDF/EU. The Accreditation as Center of Excellence Severo Ochoa CEX 2021-001189-S funded by MCIU/AEI/10.13039/501100011033 is also fully acknowledged.
Walter Randazzo
semanticscholar +4 more sources
Biomaterials, 2020 Epithelial organoids derived from human donor tissues are important tools in fields ranging from regenerative medicine to drug discovery. Organoid culture requires expansion of stem/progenitor cells in Matrigel, a tumor-derived extracellular matrix (ECM).
Victor Hernandez‐Gordillo +9 more
semanticscholar +7 more sources
Human Sapovirus Replication in Human Intestinal Enteroids
Journal of Virology, 2023 Human sapoviruses (HuSaVs) are a frequent but overlooked cause of acute gastroenteritis, especially in children. Little is known about this pathogen, whose successful in vitro cultivation was reported only recently, in a cancer cell-derived line ...
Gabriel Euller-Nicolas +8 more
semanticscholar +5 more sources
Infant and Adult Human Intestinal Enteroids are Morphologically and Functionally Distinct [PDF]
bioRxiv, 2023 Background & Aims Human intestinal enteroids (HIEs) are gaining recognition as physiologically relevant models of the intestinal epithelium. While HIEs from adults are used extensively in biomedical research, few studies have used HIEs from infants ...
Grace O. Adeniyi-Ipadeola +15 more
openalex +2 more sources
Organoid and Enteroid Modeling of Salmonella Infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2018 Salmonella are Gram-negative rod-shaped facultative anaerobic bacteria that are comprised of over 2,000 serovars. They cause gastroenteritis (salmonellosis) with headache, abdominal pain and diarrhea clinical symptoms. Salmonellosis brings a heavy burden
Yuebang Yin, Daoguo Zhou, Daoguo Zhou
doaj +10 more sources
Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis [PDF]
Molecular Metabolism, 2021 Objective: The mechanisms behind the efficacy of bariatric surgery (BS) for treating obesity and type 2 diabetes, particularly with respect to the influence of the small bowel, remain poorly understood.
Nesrin M. Hasan +10 more
doaj +3 more sources
Use of Human Intestinal Enteroids to Detect Human Norovirus Infectivity [PDF]
Emerging Infectious Diseases, 2019 Tools to detect human norovirus infectivity have been lacking. Using human intestinal enteroid cultures inoculated with GII.Pe-GII.4 Sydney–infected fecal samples, we determined that a real-time reverse transcription PCR cycle threshold cutoff of 30 may ...
Martin Chi-Wai Chan +5 more
doaj +4 more sources
31 Development of Functional Microfold (M) Cells From Intestinal Stem Cells in Primary Human Enteroids [PDF]
, 2016 Background & aimsIntestinal microfold (M) cells are specialized epithelial cells that act as gatekeepers of luminal antigens in the intestinal tract.
Joshua D. Rouch +11 more
openalex +6 more sources
Optimizing Human Intestinal Enteroids for Environmental Monitoring of Human Norovirus
Food and Environmental Virology, 2021 Human noroviruses (HuNoV) are the leading cause of gastrointestinal illness and environmental monitoring is crucial to prevent HuNoV outbreaks. The recent development of a HuNoV cell culture assay in human intestinal enteroids (HIEs) has enabled detection of infectious HuNoV.
Katie N Overbey +3 more
semanticscholar +4 more sources