Results 41 to 50 of about 93,317 (199)

New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids. [PDF]

mSphere, 2021
Ettayebi K, Tenge VR, Cortes-Penfield NW, Crawford SE, Neill FH, Zeng XL, Yu X, Ayyar BV, Burrin D, Ramani S, Atmar RL, Estes MK.   +11 more
europepmc   +2 more sources

Human intestinal enteroids platform to assess the infectivity of gastroenteritis viruses in wastewater

Water Research
Fecal-orally transmitted gastroenteritis viruses, particularly human noroviruses (HuNoVs), are a public health concern. Viral transmission risk through contaminated water results underexplored as they have remained largely unculturable until recently and the robust measuring of gastroenteritis viruses infectivity in a single cell line is challenging ...
Noelia Carmona‐Vicente, Annamaria Pandiscia, Cristina Santiso-Bellón, Alba Pérez‐Cataluña, Jesús Rodríguez‐Díaz, Verónica Costantini, Javier Buesa, Jan Vinjé, Glòria Sánchez, Walter Randazzo   +9 more
semanticscholar   +6 more sources

Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection. [PDF]

J Biol Chem, 2020
Rimkute I, Thorsteinsson K, Henricsson M, Tenge VR, Yu X, Lin SC, Haga K, Atmar RL, Lycke N, Nilsson J, Estes MK, Bally M, Larson G.   +12 more
europepmc   +3 more sources

Overcoming host restrictions to enable continuous passaging of human noroviruses in human intestinal enteroids [PDF]

bioRxiv
Gurpreet Kaur, Sue E. Crawford, Sasirekha Ramani, B. Vijayalakshmi Ayyar, Aaya Boussattach, Xi‐Lei Zeng, Robert L. Atmar, Hoa Nguyen Phuc, Cristian Coarfa, Mary K. Estes   +9 more
openalex   +2 more sources

Cover 1 - Enteroendocrine Cells in Human Intestinal Enteroids

Cellular and Molecular Gastroenterology and Hepatology, 2019

openalex   +2 more sources

Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids. [PDF]

Biomaterials, 2020
Hernandez-Gordillo V, Kassis T, Lampejo A, Choi G, Gamboa ME, Gnecco JS, Brown A, Breault DT, Carrier R, Griffith LG.   +9 more
europepmc   +2 more sources

Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology [PDF]

Journal of Biological Chemistry, 2015
Identification of Lgr5 as the intestinal stem cell marker as well as the growth factors necessary to replicate adult intestinal stem cell division has led to the establishment of the methods to generate "indefinite" ex vivo primary intestinal epithelial cultures, termed "mini-intestines." Primary cultures developed from isolated intestinal crypts or ...
Nicholas C. Zachos, Olga Kovbasnjuk, Jennifer Foulke‐Abel, Julie In, Sarah E. Blutt, Hugo R. de Jonge, Mary K. Estes, Mark Donowitz   +7 more
openalex   +3 more sources

Transcytosis of IgA Attenuates Salmonella Invasion in Human Enteroids and Intestinal Organoids

Infection and Immunity, 2022
Secretory IgA (SIgA) is the most abundant antibody type in intestinal secretions where it contributes to safeguarding the epithelium from invasive pathogens like the Gram-negative bacterium, Salmonella enterica serovar Typhimurium (STm).
Cait M. Costello, Graham G. Willsey, Angelene F. Richards, Jae‐Yoon Kim, Matteo Samuele Pizzuto, Stefano Jaconi, Fabio Benigni, Davide Corti, Nicholas J. Mantis, John C. March   +9 more
openalex   +4 more sources

Glycochenodeoxycholic acid and ceramide suppress the antiviral effect of 25-hydroxycholesterol against human norovirus infection in human intestinal enteroids [PDF]

bioRxiv, 2023
Wadzanai P. Mboko, Preeti Chhabra, Anna Montmayeur, Ruijie Xu, Verónica Costantini, Jan Vinjé   +5 more
openalex   +2 more sources

Targeted Profiling of Immunological Genes during Norovirus Replication in Human Intestinal Enteroids. [PDF]

Viruses, 2021
Norovirus is the leading cause of acute gastroenteritis worldwide. The pathogenesis of norovirus and the induced immune response remain poorly understood due to the lack of a robust virus culture system. The monolayers of two secretor-positive Chinese human intestinal enteroid (HIE) lines were challenged with two norovirus pandemic GII.4 Sydney strains.
Chan JCM, Mohammad KN, Zhang LY, Wong SH, Chan MC.   +4 more
europepmc   +5 more sources