Results 191 to 200 of about 22,575,443 (355)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Human Life as <i>Terra Nullius</i>: Socially Blind Engineering in Facebook's Foundational Technologies. [PDF]

Philos Technol
Magalhães JC, Couldry N.
europepmc   +1 more source

Correction to: Comparative Analysis of Mammal Genomes Unveils Key Genomic Variability for Human Life Span. [PDF]

Mol Biol Evol, 2022
europepmc   +1 more source

Comparative Analysis of Mammal Genomes Unveils Key Genomic Variability for Human Life Span. [PDF]

Mol Biol Evol, 2021
Farré X, Molina R, Barteri F, Timmers PRHJ, Joshi PK, Oliva B, Acosta S, Esteve-Altava B, Navarro A, Muntané G.   +9 more
europepmc   +1 more source

Human life course biology: A centennial perspective of scholarship on the human pattern of physical growth and its place in human biocultural evolution.

American Journal of Physical Anthropology, 2018
B. Bogin, C. Varea, M. Hermanussen, C. Scheffler   +3 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Evolution of the Human Life Cycle, Revisited. [PDF]

Am J Hum Biol
Bogin B, Smith BH.
europepmc   +1 more source

Bacterial low-abundant taxa are key determinants of a healthy airway metagenome in the early years of human life. [PDF]

Comput Struct Biotechnol J, 2022
Pust MM, Tümmler B.
europepmc   +1 more source

What is the capability approach?: its core, rationale, partners and dangers [PDF]

development theory; human development; quality of life; social values; freedom;
Gasper, D.R.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source