Results 251 to 260 of about 8,857,203 (292)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Law, Human Life and Ethical Dilemmas [PDF]
Bond Law ReviewThe Hon Justice Michael Kirby AC, CMG 2
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JAMA: The Journal of the American Medical Association, 1983
What is a human life worth? Is each human life worth the same as every other? Or does the worth of a human life depend on the following: What country, state, county, or city a person lives in? The color of a person's skin, the language spoken, the person's age, gender, or sexual preference? Whether the person: Has an IQ of 150 or less than 50? Is a
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What is a human life worth? Is each human life worth the same as every other? Or does the worth of a human life depend on the following: What country, state, county, or city a person lives in? The color of a person's skin, the language spoken, the person's age, gender, or sexual preference? Whether the person: Has an IQ of 150 or less than 50? Is a
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Ethics, 1985
Alan Donagan's position regarding the morality of taking innocent human life, that it is impermissible regardless of the wishes of the victim, is criticized by Brock who argues for a rights-based alternative. His argument appeals to the nature of persons' actual interest in life and gives them an additional element of control which they lack if a ...
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Alan Donagan's position regarding the morality of taking innocent human life, that it is impermissible regardless of the wishes of the victim, is criticized by Brock who argues for a rights-based alternative. His argument appeals to the nature of persons' actual interest in life and gives them an additional element of control which they lack if a ...
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HUMAN, LIFE, UNIVERSE: HUMAN’S LIFE WITHIN THE UNIVERSE
SCIENCE AND TECHNOLOGY EDUCATION: NEW DEVELOPMENTS AND INNOVATIONS, 2023A short paper as a scientific symposium report abstract is formed as a set of thematic mind maps for presentation during the authors’ speech and further discussion during the symposium BalticSTE2023. The reported material covers the author’s last 10 years period in working as professor emeritus at the University of Latvia, when developing his elective ...
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Human Life vs Human Personhood
1988Many are the legacies of Roe vs Wade, not the least of which, of course, is the death of more than ten million unborn children. Apart from the hideous slaughter there well may be one overwhelming effect of this Supreme Court decision that is not adverted to sufficiently, especially in the light of the future which already is building.
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2008
Human life-history patterns are characterized by slow maturation, long parental dependency, longevity, and low number of offspring. These developmental peculiarities determine the amount of parental investment in offspring and mating effort, and assign an adaptive role to postmenopausal women.
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Human life-history patterns are characterized by slow maturation, long parental dependency, longevity, and low number of offspring. These developmental peculiarities determine the amount of parental investment in offspring and mating effort, and assign an adaptive role to postmenopausal women.
openaire +1 more source