Results 251 to 260 of about 8,915,710 (312)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Law, Human Life and Ethical Dilemmas [PDF]

open access: yesBond Law Review
The Hon Justice Michael Kirby AC, CMG 2
doaj  
Some of the next articles are maybe not open access.

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The beginning of human life

Journal of Assisted Reproduction and Genetics, 1995
The beginning of human life is seen differently by different individuals, groups, cultures, and religions. Embryonic and fetal life are a continuum, within which are time sequences and points--birth of a newborn, viability, neuromaturation, implantation, and conception--that may be declared as the beginning of human life.
F K, Beller, G P, Zlatnik
openaire   +2 more sources

Rationing Human Life

JAMA: The Journal of the American Medical Association, 1983
What is a human life worth? Is each human life worth the same as every other? Or does the worth of a human life depend on the following: What country, state, county, or city a person lives in? The color of a person's skin, the language spoken, the person's age, gender, or sexual preference? Whether the person: Has an IQ of 150 or less than 50? Is a
openaire   +2 more sources

HUMAN, LIFE, UNIVERSE: HUMAN’S LIFE WITHIN THE UNIVERSE

SCIENCE AND TECHNOLOGY EDUCATION: NEW DEVELOPMENTS AND INNOVATIONS, 2023
A short paper as a scientific symposium report abstract is formed as a set of thematic mind maps for presentation during the authors’ speech and further discussion during the symposium BalticSTE2023. The reported material covers the author’s last 10 years period in working as professor emeritus at the University of Latvia, when developing his elective ...
openaire   +1 more source

Taking Human Life

Ethics, 1985
Alan Donagan's position regarding the morality of taking innocent human life, that it is impermissible regardless of the wishes of the victim, is criticized by Brock who argues for a rights-based alternative. His argument appeals to the nature of persons' actual interest in life and gives them an additional element of control which they lack if a ...
openaire   +2 more sources

Does the “Sanctity of Human Life” Doctrine Sanctify Humanness, or Life?

Cambridge Quarterly of Healthcare Ethics, 1999
No single principle is more critical to our ethical stance than the one asserting the sanctity of human life. In debates ranging from the care of anencephalic infants to the maintenance of fragile seniors, the question is, Where are the boundaries of sanctified human life?
openaire   +2 more sources

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