Results 91 to 100 of about 13,528,447 (353)

Arbeitskräftemobilität in Deutschland — Qualifikationsspezifische Befunde regionaler Wanderungs- und Pendlerströme

Raumforschung und Raumordnung, 2009
This article analyses internal labour mobility within Germany, distinguishing between migration and commuting and between different educational levels. Our results show that mobility flows in Germany are influenced mostly by differences in labour market
Nadia Granato, Anette Haas, Silke Hamann, Annekatrin Niebuhr   +3 more
doaj   +1 more source

Life cycle assessment of Swiss organic farming systems [PDF]

, 2006
The impacts of organic and integrated farming systems in Switzerland on the environment have been assessed in a comprehensive study by the life cycle assessment method. This paper reports a comparison of the treatments of the DOC experiment.
Dubois, D, Gaillard, G, Huguenin-Elie, O, Nemecek, T   +3 more
core  

Gene Therapy for Human Sensorineural Hearing Loss [PDF]

Frontiers in Cellular Neuroscience, 2019
Hearing loss is the most common sensory impairment in humans and currently disables 466 million people across the world. Congenital deafness affects at least 1 in 500 newborns, and over 50% are hereditary in nature. To date, existing pharmacologic therapies for genetic and acquired etiologies of deafness are severely limited.
Yin Ren, Yin Ren, Lukas D. Landegger, Lukas D. Landegger, Lukas D. Landegger, Konstantina M. Stankovic, Konstantina M. Stankovic, Konstantina M. Stankovic, Konstantina M. Stankovic   +8 more
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Analysis of the economic impact of cystic echinococcosis in Spain

Bulletin of the World Health Organization, 2010
OBJECTIVE: To estimate the overall economic losses due to human and animal cystic echinococcosis (CE) in Spain in 2005. METHODS: We obtained data on annual CE incidence from surveillance and abattoir records, and on CE-related treatment and productivity ...
Christine Benner, Hélène Carabin, Luisa P Sánchez-Serrano, Christine M Budke, David Carmena   +4 more
doaj  

Do We Know Why Earnings Fall with Job Displacement? [PDF]

, 2015
After being displaced from their jobs, workers experience reduced earnings for many years and are at greater risks of other problems as well. The ills suffered by displaced workers motivated several recent expansions of government programs, including the
Carrington, William J, Fallick, Bruce C
core   +1 more source

Elevated arousal at time of decision-making is not the arbiter of risk avoidance in chickens [PDF]

, 2015
The somatic marker hypothesis proposes that humans recall previously experienced physiological responses to aid decision-making under uncertainty. However, little is known about the mechanisms used by non-human animals to integrate risk perception with ...
A Bechara, A Bechara, A Bechara, AC Davies, AC Davies, AL Krain, AR Damasio, B Studer, CJ Burke, DJ McFarland, EA Crone, GF Loewenstein, HD Critchley, I Cuthill, JA Weller, JC Lowe, JL Edgar, JL Edgar, L Chittka, M Mendl, PC Trimmer, PH Zimmerman, RO Moe, RO Moe, S Korte, SL Lima, T Caraco, WJ Browne, X Cerda   +28 more
core   +4 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The present value of human life losses associated with COVID-19 and likely productivity losses averted through COVID-19 vaccination in Madagascar

BMC Public Health
Background As of 3 March 2023, Madagascar had reported 1,422 deaths from COVID-19. Up to now, there hasn't been a study to estimate the Total Present Value of Human Life lost $$\left({TPVHL}_{MADAGASCAR}\right)$$ TPVHL MADAGASCAR , productivity losses ...
Laurent Musango, Vatsiharizandry Mandrosovololona, Fidiniaina Mamy Randriatsarafara, Volahanta Malala Ranarison, Joses Muthuri Kirigia, Claude Arsène Ratsimbasoa   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source