Results 101 to 110 of about 13,528,447 (353)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Global Ecology and ConservationProtected areas have long been recognized globally as an important strategy for conserving biodiversity. However, the establishment of protected areas has often adversely impacted local livelihoods, particularly where people and their livelihoods are ...
Juma J. Kegamba +5 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Wage Losses of Displaced Workers in France and the US? [PDF]
This paper develops a theoretical search framework to analyse the wage losses experienced by displaced workers. We underline the importance of accounting for two different sources of wage losses whose consequences might differ, namely the loss of rents ...
Arnaud Lefranc
core
Journal of NeuroEngineering and Rehabilitation, 2019 Physical and functional losses due to aging and diseases decrease human mobility, independence, and quality of life. This study is aimed at summarizing and quantifying these losses in order to motivate solutions to overcome them with a special focus on ...
M. Grimmer +3 more
semanticscholar +1 more source
Loss of Human Capital Caused by Emigration
Studies on Russian Economic Development, 2022 Today, the question is often raised about the need to increase investment in human capital, the efficiency of its use, as well as attraction to the regions. Working on the accumulation of human capital, it is necessary to ensure that it does not "leak" from the country; especially for highly skilled workers. The article considers the features of modern
openaire +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Restructuring in Ireland [PDF]
, 2013 Ireland’s economy is relatively small and trade-dependent and is considered one of the most globalised and open in the world. It suffered disproportionate damage following the 2008–9 global recession as a large construction and financial sector bust ...
Eurofound
core +1 more source
Evidence of human influence on Northern Hemisphere snow loss
NatureDocumenting the rate, magnitude and causes of snow loss is essential to benchmark the pace of climate change and to manage the differential water security risks of snowpack declines1–4.
Alexander R. Gottlieb, J. Mankin
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source