Results 111 to 120 of about 13,528,447 (353)

The cost of job loss [PDF]

open access: yes, 2015
In this paper we develop and quantitatively assess a tractable equilibrium search model of the labour market to analyse the long-term wage costs of a job loss.
Burdett, Ken   +2 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Does the color of the collar matter? Firm specific human capital and post-displacement outcomes [PDF]

open access: yes
We investigate whether the costs of job displacement differ between blue collar and white collar workers. In the short run earnings and employment losses are substantial for both groups but stronger for white collar workes.
Andrea Ichino   +4 more
core   +3 more sources

Socially significant infections as the causes of losses in quality of main components of public health in Russia

open access: yesСибирский научный медицинский журнал
In Russia, more and more attention is being paid to strengthening public health as a system that covers all spheres of human life. Meanwhile, the medical and social causes of human resources losses as a foundation of public health have not been ...
Z. M. Zagdyn
doaj   +1 more source

Cloning Entangled Qubits to Scales One Can See

open access: yes, 2010
By amplifying photonic qubits it is possible to produce states that contain enough photons to be seen with a human eye, potentially bringing quantum effects to macroscopic scales [1].
Gisin, Nicolas   +4 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Productivity loss due to premature mortality caused by blood cancer: a study based on patients undergoing stem cell transplantation

open access: yesGaceta Sanitaria, 2015
Introduction: Stem cell transplantation has been used for many years to treat haematological malignancies that could not be cured by other treatments. Despite this medical breakthrough, mortality rates remain high.
Marta Ortega-Ortega   +4 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Assessing ecosystem service losses—A review of progress and problems

open access: yesResources, Environment and Sustainability
The assessment of ecosystem service losses is crucial for ecological impact assessment and the practice of ecological compensation restoration projects.
Hanjie Wang   +4 more
doaj   +1 more source

Rapidly Growing Middle Class Presents Severe Challenge for the Environment and Human Health in Asia and the Pacific [PDF]

open access: yes, 2016
Unprecedented economic growth, which has lifted millions out of poverty in Asia and the Pacific, is putting heavy pressure on ecosystems. Increasing unsustainable consumption patterns have led to worsening air pollution, water scarcity and waste ...

core  

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