Results 241 to 250 of about 2,261,504 (355)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Health Effects and Mechanisms of Inulin Action in Human Metabolism. [PDF]

Nutrients
Alonso-Allende J, Milagro FI, Aranaz P.
europepmc   +1 more source

In vitro and in vivo human metabolism and pharmacokinetics of S- and R-praziquantel. [PDF]

Pharmacol Res Perspect, 2020
Kapungu NN, Li X, Nhachi C, Masimirembwa C, Thelingwani RS.   +4 more
europepmc   +1 more source

Human disposition, metabolism and excretion of etamicastat, a reversible, peripherally selective dopamine β-hydroxylase inhibitor [PDF]

, 2013
Ana I. Loureiro, José Rocha, Carlos Fernandes‐Lopes, Teresa Nunes, Lyndon Wright, Luís Almeida, Patrício Soares‐da‐Silva   +6 more
openalex   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

The HuMet Repository: Watching human metabolism at work. [PDF]

Cell Rep
Weinisch P, Raffler J, Römisch-Margl W, Arnold M, Mohney RP, Rist MJ, Prehn C, Skurk T, Hauner H, Daniel H, Suhre K, Kastenmüller G.   +11 more
europepmc   +1 more source

Bio-sniffers and Sniff-cam based on human disease and metabolism for gaseous chemicals

, 2015
Kohji Mitsubayashi
openalex   +2 more sources

The Study of Genetically Determined Variations in the Human Metabolism of Some Drugs; Including the Use of Liver Biopsy Material [PDF]

, 1963
David A. Evans
openalex   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Response of human metabolism to ultra-low and high nicotine cigarettes based on urine metabolomics and bioinformatic analysis. [PDF]

Tob Induc Dis
Zhang M, Yang C, Gao L, Zhao Y, Shi H.
europepmc   +1 more source