Results 281 to 290 of about 8,615,950 (386)

Bibliometric and visual analysis of human microbiome-breast cancer interactions: current insights and future directions. [PDF]

Front Microbiol
Zhou Y, Jiang M, Li X, Shen K, Zong H, Lv Q, Shen B.   +6 more
europepmc   +1 more source

Advancing Predictions of Oral Drug Absorption, CYP3A4 Induction, and Transporter‐Mediated Interactions Using a Human Primary Intestinal 3D Model (EpiIntestinal™)

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate prediction of oral drug absorption in humans is essential for early drug development; however, physiologically relevant human models are lacking. This study aims to comprehensively assess the EpiIntestinal™, a human primary intestinal 3D model, for its ability to predict oral absorption (Fa), intestinal availability (Fg), CYP3A4 induction, and
Paresh P. Chothe, Andrea Whitcher‐Johnstone, Aniruddha Karve, Diane Ramsden, Niresh Hariparsad   +4 more
wiley   +1 more source

The Human Microbiome as a Therapeutic Target for Metabolic Diseases. [PDF]

Nutrients
Bui TPN.
europepmc   +1 more source

Metagenomic Identification of a Novel Salt Tolerance Gene from the Human Gut Microbiome Which Encodes a Membrane Protein with Homology to a brp/blh-Family β-Carotene 15,15′-Monooxygenase

, 2014
Eamonn P. Culligan, Roy D. Sleator, Julian R. Marchesi, Colin Hill   +3 more
openalex   +2 more sources

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

Barrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

Standardizing the approach to clinical-based human microbiome research: from clinical information collection to microbiome profiling and human resource utilization. [PDF]

Osong Public Health Res Perspect
Kim JW, Choi EC, Lee KJ.
europepmc   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

TM7 detection in human microbiome: Are PCR primers and FISH probes specific enough? [PDF]

, 2015
Maria V. Sizova, Sebastian N. Doerfert, Ekaterina Gavrish, Slava S. Epstein   +3 more
openalex   +1 more source

The human microbiome-derived antimicrobial lugdunin self-regulates its biosynthesis by a feed-forward mechanism. [PDF]

mBio
Reetz L, Schulze L, Kronenberger T, Selim KA, Schaefle T, Dema T, Zipperer A, Mößner J, Poso A, Grond S, Peschel A, Krismer B.   +11 more
europepmc   +1 more source

Early life dynamics of the human gut virome and bacterial microbiome in infants [PDF]

, 2015
Efrem S. Lim, Yanjiao Zhou, Guoyan Zhao, Irma Bauer, Lindsay Droit, I. Malick Ndao, Barbara Warner, Phillip I. Tarr, David Wang, Lori R. Holtz   +9 more
openalex   +1 more source