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Metagenomic analysis can generate hypotheses about microbiome interactions and function, yet mechanistic understanding is only possible through precise experimentation manipulating its microbiota composition. The high‐throughput isolation of microbiome members thus represents a core resource in this field of research.
Rubén Chaboy‐Cansado+6 more
wiley +1 more source
Multi‐omics analysis of gut‐organ axes reveals the high‐altitude adaptation in Tibetan chicken
The Qinghai‐Tibet Plateau is an extreme ecosystem subject to special climatic conditions that require unique adaptations for its inhabiting organisms. In addition to genetic characteristics, the gut microbiota of animals can regulate the environmental adaptation of their hosts through various gut–organ axes.
Tao Zeng+15 more
wiley +1 more source
Saliva MicroAge is a machine learning‐based model designed to estimate biological age and assess health status using globally sourced salivary microbiome data. Trained on 4532 healthy samples, the model achieves high accuracy in predicting chronological age and captures health‐related deviations (MicroAgeGap) in various diseases.
Tiansong Xu+13 more
wiley +1 more source
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma+13 more
wiley +1 more source
Impact of Toxoplasma gondii and Human Microbiome on Suicidal Behavior: A Systematic Review. [PDF]
Zerekidze A+6 more
europepmc +1 more source
ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome. [PDF]
Hirsch P+10 more
europepmc +1 more source
CoCas9 is a compact nuclease from the human microbiome for efficient and precise genome editing. [PDF]
Pedrazzoli E+15 more
europepmc +1 more source
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Pediatric Allergy and Immunology, 2020
AbstractHuman microbiome contributes to critical functions that impact health and disease. It influences the development of the immune system, and the pathogenesis of immunological disorders included allergy. While it is easy to understand how airway microbiome, influencing local inflammation and immune activity, could contribute to shaping asthma ...
Montecchiani V., Fanos V.
openaire +4 more sources
AbstractHuman microbiome contributes to critical functions that impact health and disease. It influences the development of the immune system, and the pathogenesis of immunological disorders included allergy. While it is easy to understand how airway microbiome, influencing local inflammation and immune activity, could contribute to shaping asthma ...
Montecchiani V., Fanos V.
openaire +4 more sources
Translating the human microbiome
Nature Biotechnology, 2013absent
Brown, James+8 more
openaire +3 more sources