Results 181 to 190 of about 52,078 (245)

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Sensory contribution of emollient cascades in skin creams evaluated by CATA analysis

International Journal of Cosmetic Science, EarlyView.
This work includes emulsion composition and sensory analysis methodology, emollient cascade theory and study results. This study demonstrates how deliberate structuring of emollient cascades can be used as a formulation strategy to modulate both perceived skin feel and product appearance within emulsified systems.
Anna Gerken, Ellen Libby, Paolo Vigilante, Raihaanah Safee, Mihaly Szoboszlai, Gabriella Baki   +5 more
wiley   +1 more source

Gender Justice in the Triple Planetary Crisis: A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To identify and report how gender justice is conceptualised and discussed in contemporary health literature in relation to the Triple Planetary Crisis of climate change, pollution and biodiversity loss, with a particular focus on the experiences of women and gender‐diverse populations, and the representation of nurses and other healthcare ...
Catelyn Richards, Micah Peters, Julia Charalambous, Lila Singh‐Peterson, Lucy Osborn, Aletha Ward, Jessica LeClair, Tracy Levett‐Jones   +7 more
wiley   +1 more source

Targeting the miR‐224‐5p/PTEN pathway: A previously under‐characterized strategy to attenuate mesangial cell injury and predict prognosis in diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
Serum miR‐224‐5p levels are progressively elevated in diabetic nephropathy (DN) and serve as an independent predictor of a decline in eGFR of ≥30% over 2 years. Mechanistically, miR‐224‐5p directly targets PTEN 3’‐UTR, suppressing PTEN and the activation of the AKT pathway in high‐glucose‐stimulated mesangial cells.
Yanxia Gao, Xiaohui Zhang, Peng Lu, Qiang Wang   +3 more
wiley   +1 more source

Secondary cartilage in the murine medial pterygoid plate has a critical role in the pathfinding of the tensor veli palatini

Journal of Anatomy, EarlyView.
The development of the medial pterygoid plate (MPP) is followed in mouse embryos, highlighting its neural crest origin and complex development via both endochondral and membranous ossification. Using transgenic mice, the secondary cartilage of the MPP is shown to direct the path of the tensor veli palatini.
Luke A. Barlow, Emi Nomura, Abigail S. Tucker   +2 more
wiley   +1 more source

Peasant Movements and the Fourth Transformation in Mexico: What Does the Theory of Collective Empowerment Tell Us?

Journal of Agrarian Change, EarlyView.
ABSTRACT This article examines peasant and Indigenous movements in Mexico since Morena's rise to power in 2018 through the lens of collective empowerment theory, a theory of political‐cultural formation. Beyond offering an empirical assessment, the theory is refined and formalized through an analysis of these movements and their relationship to ...
Gerardo Otero
wiley   +1 more source

Impact of Access to Pasteurised Donor Human Milk on Rates of Necrotising Enterocolitis in Neonatal Units in Australia: A Cohort Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background and Aim In 2018, a pasteurised donor human milk (PDHM) service was established within Australia's national blood service, Lifeblood, and subsequently expanded to a national service. Before 2018, five milk banks operated in Australia, but most infants admitted to Australian neonatal intensive care units (NICUs) still did not have ...
Laura D. Klein, Kei Lui, Abrar A. Chughtai, David A. Osborn, Robert Guaran, Andrew J. McPhee, Ulrike Brandenberg, Ian Callander, Lisa H. Amir, Christine Sulfaro, Richard Brown, David O. Irving, Veronica Hoad, Joanne Pink, Vanessa Clifford, Australian and New Zealand Neonatal Network, Scott Morris, Peter Schmidt, Manbir Chauhan, Larissa Korostenski, Mary Sharp, Steven Resnick, Rebecca Thomas, Tobias Strunk, Jacqueline Stack, Pita Birch, Tori Oliver, Dan Casalaz, Jim Holberton, Alice Stewart, Rod Hunt, Kenneth Tan, Lucy Cooke, Lyn Downe, Jonathan Davis, Michael Stewart, Andrew Berry, Leah Hickey, Mantho Kgosiemang, Tony De Paoli, Naomi Spotswood, Srinivas Bolisetty, Kei Lui, Eveline Staub, Mark Greenhalgh, Pieter Koorts, Sue Jacobs, Amy Keir, Clare Collins, Andrew Numa, Hazel Carlisle, Nadia Badawi, Himanshu Popat, Gary Alcock, Melissa Luig, Alison Kent, Bronwyn Dixon, Brian Darlow, Peter Fowlie, Andrew Kelly, Guy Bloomfield, Mariam Buksh, Malcolm Battin, Jutta van den Boom, Helen Miller, Angelica Allermo‐Fletcher, Claire Jacobs, Victor Samuel Rajadurai, Simon Lam, Georgina Chambers, David Barker, Anjali Dhawan, Natalie Merida, Denise Harrison, Kenneth Tan, Nicola Austin, Barbara Bajuk, Luke Jardine, Michael Meyer, Tim Schindler, Michael Stark, Tobias Strunk, Javeed Travadi   +82 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

How Institutions Shape the Effects of Agricultural Cooperatives on Their Members

Kyklos, EarlyView.
ABSTRACT Agricultural cooperatives represent a promising way of improving the quality of life of half a billion smallholders, who account for the vast majority of the world's food production. Yet, little is known about the institutional factors that explain the potential benefits of being a member of a cooperative.
Simon Cornée, Madeg Le Guernic, Damien Rousselière   +2 more
wiley   +1 more source