Results 41 to 50 of about 1,543,903 (270)

Mobilization of Human Resources [PDF]

open access: yes, 2011
This chapter looks at the role graduates play in the mobilization of human resources. A distinction is drawn between graduates’ mobilization of their own capabilities and their role in mobilizing the capacities of others working in the same organization.
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Predicting commuter flows in spatial networks using a radiation model based on temporal ranges

open access: yes, 2014
Understanding network flows such as commuter traffic in large transportation networks is an ongoing challenge due to the complex nature of the transportation infrastructure and of human mobility.
Ercsey-Ravasz, Mária   +4 more
core   +1 more source

Unravelling daily human mobility motifs [PDF]

open access: yesJournal of The Royal Society Interface, 2013
Human mobility is differentiated by time scales. While the mechanism for long time scales has been studied, the underlying mechanism on the daily scale is still unrevealed. Here, we uncover the mechanism responsible for the daily mobility patterns by analysing the temporal and spatial trajectories of thousands of persons as individual networks.
Schneider, Christian M.   +4 more
openaire   +5 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

STAR: A Concise Deep Learning Framework for Citywide Human Mobility Prediction

open access: yes, 2019
Human mobility forecasting in a city is of utmost importance to transportation and public safety, but with the process of urbanization and the generation of big data, intensive computing and determination of mobility pattern have become challenging. This
Su, Han, Wang, Hongnian
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Beyond Seasickness: A Motivated Call for a New Motion Sickness Standard across Motion Environments

open access: yesVibration, 2022
Motion sickness is known under several names in different domains, such as seasickness, carsickness, cybersickness, and simulator sickness. As we will argue, these can all be considered manifestations of one common underlying mechanism.
Jelte E. Bos   +2 more
doaj   +1 more source

Empowering and assisting natural human mobility: The simbiosis walker [PDF]

open access: yes, 2011
This paper presents the complete development of the Simbiosis Smart Walker. The device is equipped with a set of sensor subsystems to acquire user-machine interaction forces and the temporal evolution of user's feet during gait.
Frizera A.   +8 more
core   +4 more sources

Understanding individual human mobility patterns [PDF]

open access: yesNature, 2008
Supporting Webpage: http://www.nd.edu/~mgonza16/Marta'sHomepage_files/nature2008/research ...
Gonzalez, M. C.   +2 more
openaire   +3 more sources

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