Incorporating social contact data in spatio-temporal models for infectious disease spread [PDF]
Biostatistics (2017); 18(2):338-351, 2015 Routine public health surveillance of notifiable infectious diseases gives rise to weekly counts of reported cases -- possibly stratified by region and/or age group. We investigate how an age-structured social contact matrix can be incorporated into a spatio-temporal endemic-epidemic model for infectious disease counts.
arxiv +1 more source
Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity [PDF]
, 2022 Murine norovirus (MNoV) is a model for human norovirus and for interrogating mechanisms of viral tropism and persistence.
Alfajaro, Mia Madel +11 more
core +2 more sources
Human norovirus transmission and evolution in a changing world [PDF]
Nature Reviews Microbiology, 2016 Norovirus infections are a major cause of gastroenteritis, and outbreaks occur frequently. Several factors are currently increasing the challenge posed by norovirus infections to global health, notably the increasing number of infections in immunocompromised individuals, who are more susceptible to disease, and the globalization of the food industry ...
de Graaf, Miranda +2 more
openaire +4 more sources
Acceptability of temporary suspension of visiting during norovirus outbreaks:investigating patient, visitor and public opinion [PDF]
, 2016 Background Noroviruses are a leading cause of outbreaks globally and the most common cause of service disruption due to ward closures. Temporary suspension of visiting (TSV) is increasingly a recommended public health measure to reduce exposure ...
Adams +28 more
core +2 more sources
Molecular Evolution of Human Norovirus GII.2 Clusters
Frontiers in Microbiology, 2021 BackgroundThe human norovirus GII.2 outbreak during the 2016–2017 winter season was of unprecedented scale and geographic distribution.MethodsWe analyzed 519 complete VP1 gene sequences of the human norovirus GII.2 genotype sampled during the 2016–2017 ...
Xingguang Li +4 more
doaj +1 more source
FaiR-IoT: Fairness-aware Human-in-the-Loop Reinforcement Learning for Harnessing Human Variability in Personalized IoT [PDF]
IoTDI 2021: Proceedings of the International Conference on
Internet-of-Things Design and Implementation, 2021 Thanks to the rapid growth in wearable technologies, monitoring complex human context becomes feasible, paving the way to develop human-in-the-loop IoT systems that naturally evolve to adapt to the human and environment state autonomously. Nevertheless, a central challenge in designing such personalized IoT applications arises from human variability ...
arxiv +1 more source
Comparing Human Norovirus Surrogates: Murine Norovirus and Tulane Virus
Journal of Food Protection, 2013 Viral surrogates are widely used by researchers to predict human norovirus behavior. Murine norovirus (MNV) is currently accepted as the best surrogate and is assumed to mimic the survival and inactivation of human noroviruses. Recently, a new calicivirus, the Tulane virus (TV), was discovered, and its potential as a human norovirus surrogate is being
Kalmia E. Kniel, Kirsten A. Hirneisen
openaire +2 more sources
The norovirus NS3 protein is a dynamic lipid- and microtubule-associated protein involved in viral RNA replication [PDF]
, 2017 Norovirus (NoV) infections are a significant health burden to society, yet the lack of reliable tissue culture systems has hampered the development of appropriate antiviral therapies.
Cotton, Ben T +6 more
core +2 more sources
Development of Antibody-Fragment–Producing Rice for Neutralization of Human Norovirus
Frontiers in Plant Science, 2021 Human norovirus is the leading cause of acute nonbacterial gastroenteritis in people of all ages worldwide. Currently, no licensed norovirus vaccine, pharmaceutical drug, or therapy is available for the control of norovirus infection.
Ai Sasou +23 more
doaj +1 more source
Human norovirus binding to select bacteria representative of the human gut microbiota. [PDF]
PLoS ONE, 2017 Recent reports describe the ability of select bacterial strains to bind human norovirus, although the specificity of such interactions is unknown. The purpose of this work was to determine if a select group of bacterial species representative of human ...
Erin A Almand +3 more
doaj +1 more source