Results 121 to 130 of about 9,786,103 (295)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
LearnPCC scientific conference held in Gothenburg, Sweden, on 12–13 December 2024The inaugural LearnPCC scientific conference was held in Gothenburg, Sweden, on 12–13 December 2024. Organised by the Centre for Person-Centred Care (GPCC) at the University
LearnPCC Conference 1 2024 Göteborg
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, 2017 The person-item map displays the location of person abilities and item difficulties respectively along the same latent dimension. The person parameter is located on the scale from left (mild impairment) to right (severe impairment).
Cécile Proust-Lima (3612287) +11 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The second Global Conference on Person-Centred Care: Bridging Practice, Organisation and Governance
This is the abstract book for the second Global Conference on Person-Centred Care (GCPCC) with the theme Bridging Practice, Organisation and Governance.
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VIAŢA FIINŢEI UMANE ŞI LIMITELE ÎN INTERIORUL CĂRORA ACEASTA SE BUCURĂ DE OCROTIRE PENALĂ
Studia Universitatis Moldaviae: Stiinte Sociale, 2016 În studiul de faţă se elucidează, inter alia, că viaţa fiinţei umane capătă o nouă abordare în ştiinţele medicale; drepturmare, sub aspect temporal, viaţa fiinţei umane începe până la naştere şi încetează odată cu decesul.
Dumitru BULIGA
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Litigants in Person in Private Family Law Cases [PDF]
, 2014 This study was designed to develop the evidence base on litigants in person in private family law cases, including their behavioural drivers, experiences and support needs, and impact on the court prior to the implementation of legal aid reforms in April
Miles, J +23 more
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Консультативная психология и психотерапия, 2012 The author of the article suggests and considers a number of promising directions of dealing with theological concept of human being as image of God in anthropological models of Christian psychology aimed at solving actual theoretical and practical ...
Chursanov S.A.
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