Results 171 to 180 of about 5,283,554 (314)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Social Potential Fields

open access: yes, 2008
Introduction Methodology Results Code Documentation References INTRODUCTION Robot Motion Planning is the problem of planning a path from a initial configuration to a goal configuration for the robot avoiding collisions with the obstacles in between. The
Social Potential Fields   +1 more
core  

Assessing Evidence to Guide Primary Prevention of Pathogen X. [PDF]

open access: yesEmerg Infect Dis
Holmes I   +6 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Potential Impacts of Climate Change on Waste Management in Ilorin city Nigeria

open access: yes, 2012
Ilorin is one of the major cities in Nigeria today and its growing capacity in both socio-economic affiliations is commendable However the city is potently polluted with heaps of refuse that are occasionally caused traffic hold-up in places in the ...
Dr.Y.A.Ahmed
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Exploration of Students' Mathematical Literacy Abilities in Visualizing Division of Fraction

open access: yesIndoMath
The aim of this research was to find out how prospective mathematics teachers can visualize the form of fractional division operations based on mathematical literacy skills. This research includes qualitative research with descriptive methods. This study
Rohmah Indahwati   +2 more
doaj  

Yellow fever outbreak potential in Djibouti, Somalia and Yemen: a mathematical modelling study. [PDF]

open access: yesBMC Glob Public Health
Fraser K   +5 more
europepmc   +1 more source

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