Results 91 to 100 of about 690,254 (288)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Scientific ReportsConventional radiography (CR) is primarily utilized for fracture diagnosis. Artificial intelligence (AI) for CR is a rapidly growing field aimed at enhancing efficiency and increasing diagnostic accuracy.
Julius Husarek +6 more
doaj +1 more source
Getting the word out: Neural correlates of enthusiastic message propagation
Frontiers in Human Neuroscience, 2012 What happens in the mind of a person who first hears a potentially exciting idea? We examined the neural precursors of spreading ideas with enthusiasm, and dissect enthusiasm into component processes that can be identified through automated linguistic ...
Emily eFalk +3 more
doaj +1 more source
Human Papillomavirus Vaccination and Human Papillomavirus–Related Cancer Rates
JAMA Network OpenImportanceTo inform the design and implementation of targeted interventions to reduce the future burden of human papillomavirus (HPV)–related cancers in Texas, it is necessary to examine the county and health service region (HSR) levels of (1) the proportion of children and teenagers aged 9 to 17 years who initiated and were up to date for HPV ...
Adekanmbi, Victor +7 more
openaire +3 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Psychosocial Risks of Storing and Using Human Tissues in Research [PDF]
, 1997 Dr. Merz argues that genetics technology makes it more compelling that researchers plan more carefully for the collection and disposition of information derived from subjects\u27 tissues and ...
Merz, Jon F.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
InformationThe proliferation of user-generated content in today’s digital landscape has further increased dependence on online reviews as a source for decision-making in the hospitality industry.
Patricia Nnanna +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
An assessment system for rating scientific journals in the field of ergonomics and human factors [PDF]
A method for selecting and rating scientific and professional journals representing the discipline of ergonomics and human factors is proposed. The method is based upon the journal list, impact factors and citations provided by the Institute of ...
Dul, J., Karwowski, W.
core +1 more source