Results 61 to 70 of about 690,254 (288)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Providing behaviour awareness in collaborative project courses [PDF]

open access: yes, 2016
Several studies show that awareness mechanisms can contribute to enhance the collaboration process among students and the learning experiences during collaborative project courses. However, it is not clear what awareness information should be provided to
Medina Medina, Esunly   +3 more
core   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Controlled-Rate Freezing of Human ES Cells

open access: yesBioTechniques, 2005
A significant obstacle to using human embryonic stem cells (hESCs) arises from extremely poor survival associated with freezing, typically in the range of 1%. This report describes a slow controlled-rate freezing technique commonly used for mammalian embryo cryopreservation.
Carol B. Ware   +2 more
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Differences in configural processing for human versus android dynamic facial expressions

open access: yesScientific Reports, 2023
Humanlike androids can function as social agents in social situations and in experimental research. While some androids can imitate facial emotion expressions, it is unclear whether their expressions tap the same processing mechanisms utilized in human ...
Alexander Diel   +3 more
doaj   +1 more source

Reinforcement Learning for Bandit Neural Machine Translation with Simulated Human Feedback

open access: yes, 2017
Machine translation is a natural candidate problem for reinforcement learning from human feedback: users provide quick, dirty ratings on candidate translations to guide a system to improve.
Boyd-Graber, Jordan   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Virtual Patients Using Large Language Models: Scalable, Contextualized Simulation of Clinician-Patient Dialogue With Feedback

open access: yesJournal of Medical Internet Research
BackgroundVirtual patients (VPs) are computer screen–based simulations of patient-clinician encounters. VP use is limited by cost and low scalability. ObjectiveWe aimed to show that VPs powered by large language models
David A Cook   +4 more
doaj   +1 more source

Environmental risks to humans, the first database of valence and arousal ratings for images of natural hazards

open access: yesScientific Data, 2022
Measurement(s) valence and arousal Technology Type(s) human ratings Factor Type(s) natural hazards Sample Characteristic - Organism Homo sapiens Sample Characteristic - Environment anthropogenic ...
Giulia Prete, Bruno Laeng, Luca Tommasi
doaj   +1 more source

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