Results 151 to 160 of about 6,443,406 (299)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Testing ethical disagreement on ancestral human remains in museums. [PDF]

Int J Cult Prop
Francis E, Asker C, Tischler V.
europepmc   +1 more source

Author Correction: Human remains from Arma di Nasino (Liguria) provide novel insights into the paleoecology of early Holocene foragers in northwestern Italy. [PDF]

Sci Rep, 2023
Sparacello VS, Goude G, Varalli A, Dori I, Gravel-Miguel C, Riel-Salvatore J, Palstra SWL, Moggi-Cecchi J, Negrino F, Starnini E.   +9 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Who Speaks for the Dead? Of Communities and Stewardship in Legacy Collections of Human Remains. [PDF]

Am J Biol Anthropol
Jackson FLC, Auerbach BM.
europepmc   +1 more source

Osteological, multi-isotope and proteomic analysis of poorly-preserved human remains from a Dutch East India Company burial ground in South Africa. [PDF]

Sci Rep, 2023
Olszewski J, Hall RA, Kootker LM, Oldham NJ, Layfield R, Shaw B, Derksen L, Manders M, Hart T, Schrader SA.   +9 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Examination of Human Skeletal Remains and Artifacts from el-Qantir, Egypt [PDF]

, 2011
Stephen, Emily
core   +1 more source

Earliest evidence for intentional cremation of human remains in Africa. [PDF]

Sci Adv
Cerezo-Román JI, Sawchuk E, Schilt F, Bertacchi A, Buckley G, Chibisa E, Fahey BP, Falchenberg SGH, Kaliba P, Kennett DJ, Mercader J, Pargeter J, Stock J, Szymanski R, Thompson JC.   +14 more
europepmc   +1 more source

Postmortem Skeletal Microbial Community Composition and Function in Buried Human Remains. [PDF]

mSystems, 2022
Emmons AL, Mundorff AZ, Hoeland KM, Davoren J, Keenan SW, Carter DO, Campagna SR, DeBruyn JM.   +7 more
europepmc   +1 more source