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Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source
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Human Remains Logistics

2023
Life and death are unique phenomena. Death is inevitable; thus, people will eventually become consumers of end-of-life products and services. The death care industry is currently facing radical challenges. The death-denying attitude can severely undermine the examination of the death care industry.
Yui-yip Lau   +2 more
openaire   +1 more source

On human remains

ACM Transactions on Computer-Human Interaction, 2010
Creating digital archives of personal and family artifacts is an area of growing interest, but which seemingly is often not supported by a thorough understanding of current home archiving practice. In this article we seek to excavate the home archive, exploring those things that people choose to keep rather than simply accumulate.
Kirk DS, Sellen A
openaire   +2 more sources

Archeological Human Remains

Current Anthropology, 1998
Recent developments regarding the repatriation of human skeletal remains have raised questions of profound significance for both archeologists and anthropologists. The various responses to these questions have tended to focus on the implications of these developments for the future of the academic disciplines and skirted the ethical issues at stake. In
D. Gareth Jones, Robyn J. Harris
openaire   +1 more source

Human remains

2023
Chris Chinnock, Don Walker
openaire   +2 more sources

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce   +2 more
exaly  

Human Remains

2011
John W. Verano, Jack Rossen
openaire   +1 more source

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