Results 131 to 140 of about 92,760,831 (252)

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Evaluating perspectives and attitudes towards the South African medical internship programme

open access: yesBMC Medical Education
South Africa’s healthcare system faces a quadruple burden of disease and marked social inequalities, necessitating an increased number of well-trained medical personnel.
R. Boden   +3 more
doaj   +1 more source

Strengthening national and subnational departments for human resources development

open access: yes, 2008
60 p. : ill ; 24 cm.There is a growing health workforce crisis in many countries. In the WHO Eastern Mediterranean Region, the disparity in supply and demand, geographic maldistribution in urban and rural settings and imbalance in the number of different
World Health Organization. Regional Office for the Eastern Mediterranean
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Workload indicators of staffing need (WISN): selected country implementation experiences

open access: yes, 2016
33 p.This publication documents the implementation of the Workload Indicators of Staffing Need (WISN) methodology in selected countries and describes the World Health Organization’s approach to supporting evidence-based health workforce planning ...
World Health Organization
core  

Meeting of the Ad Hoc Working Group on Human Resources for Health in Small Countries in the European Region: progress, action and next steps, 27–28 January 2022 (in-person and online)

open access: yes, 2022
iv, 17 p.Two years into the COVID-19 pandemic, health workforces (HWF) in small countries were faced with huge demands, having to address challenges related to a relatively limited capacity in human resources for health.
World Health Organization. Regional Office for Europe
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

HHRU 95:4

open access: yes, 1995
PRODUCTION UPDATE 94 describes the training programs for selected health and human services personnel in British Columbia. It is the first version of a new series which will be produced in the interim year, alternating with the regular biennial ...
University of British Columbia. Health Human Resources Unit
core   +1 more source

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