Results 151 to 160 of about 12,430,295 (425)
Do LLMs exhibit demographic parity in responses to queries about Human Rights? [PDF]
arXivThis research describes a novel approach to evaluating hedging behaviour in large language models (LLMs), specifically in the context of human rights as defined in the Universal Declaration of Human Rights (UDHR). Hedging and non-affirmation are behaviours that express ambiguity or a lack of clear endorsement on specific statements.
arxiv
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Using Thematic Hearings at the Inter-American Human Rights Commission to Advance U.S. Human Rights Accountability: A Resource for the Bringing Human Rights Home Lawyers\u27 Network [PDF]
, 2016 As U.S. social justice advocates increasingly turn to the Inter‐American Commission on Human Rights (the “IACHR” or the “Commission”) as a tool to advance domestic social justice advocacy, there has been significant growth in the number of requests for ...
Human Rights Institute,
core +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Human Rights Institute Annual Report 2014-2015 [PDF]
, 2015 The Human Rights Institute sits at the heart of human rights teaching, practice, and scholarship at Columbia Law School. Founded in 1998 by the late Professor Louis Henkin, the Institute draws on the Law School’s deep human rights tradition to support ...
Human Rights Institute,
core +1 more source
The Populist Challenge to Human Rights
, 2017 The nationalistic, xenophobic, misogynistic, and explicitly anti-human rights agenda of many populist political leaders requires human rights proponents to rethink many longstanding assumptions.
Philip Alston
semanticscholar +1 more source
Molecular Oncology, EarlyView.Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source
Accession Of The Communities To The European Convention On Human Rights: Commission Memorandum [PDF]
, 1979 Kim Economides, Joseph H. H. Weiler
openalex +1 more source
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source