Results 151 to 160 of about 12,497,859 (378)
The “Everyday Politics” of IDP Protection in Karen State
While international humanitarian access in Burma has opened up over the past decade and a half, the ongoing debate regarding the appropriate relationship between politics and humanitarian assistance remains unresolved.
Stephen Hull
doaj +1 more source
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
International Human Rights are Taking Hold in U.S. States, Cities, and Towns [PDF]
New York, NY (December 10, 2012) – Incorporating human rights into local policies and decision-making leads to effective, sustainable, and responsive policies, according to a new report released today by Columbia Law School’s Human Rights ...
Human Rights Institute,
core +1 more source
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Human Rights for the Digital Age [PDF]
The emergence of digital technology has fundamentally transformed all facets of human existence, posing important queries about the safeguarding and implementation of human rights in the digital domain. The research focuses on important topics including privacy, freedom of speech, and information access.
arxiv
Civilian Impact of Covert Drone Operations Overlooked [PDF]
WASHINGTON, DC Sept. 30, 2012 — As US covert drone strikes become more entrenched as an accepted counterterrorism strategy, the US government needs to conduct a thorough accounting of the impact on civilians, said a new report released today by Columbia ...
Human Rights Clinic,
core +1 more source
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Debunking Robot Rights Metaphysically, Ethically, and Legally [PDF]
In this work we challenge arguments for robot rights on metaphysical, ethical and legal grounds. Metaphysically, we argue that machines are not the kinds of things that may be denied or granted rights. Building on theories of phenomenology and post-Cartesian approaches to cognitive science, we ground our position in the lived reality of actual humans ...
arxiv
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source