Results 201 to 210 of about 3,886,019 (315)

Contextualizing Universal Human Rights: An Integrated Human Rights Framework for ASEAN [PDF]

, 2015
Wang, Yvonne Xin
core   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

To Fund or Not to Fund?: Human Rights Guardrails for Financing Planned Relocations of Communities Facing the Climate Crisis

AJIL Unbound
Charlotte Finegold, Erica Bower
doaj   +1 more source

Transforming through democracy, human rights, and sustainable development at the 5th National Conference on Workers' Health. [PDF]

Epidemiol Serv Saude
Maciel EL, Leão L, Dias LA, Lima DOC, Maio I.   +4 more
europepmc   +1 more source

International Investment Agreements, Human Rights, and the Path to Net-Zero: What Role for Corporate Codes? [PDF]

Susan L. Karamanian
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Impacts of Sexual and Reproductive Health and Rights Misinformation in Digital Spaces on Human Rights Protection and Promotion: Scoping Review. [PDF]

JMIR Infodemiology
Purnat TD, Wilhelm E, Scales D, Wardle C, Bastien S, Ganatra B, Lavelanet A, Mburu G, Tamrat T, Nihlén Å.   +9 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Protection of human rights during involuntary treatment in mental healthcare services: A European perspective. [PDF]

Eur Psychiatry
Rojnic Kuzman M, Fiorillo A, Beezhold J.
europepmc   +1 more source