Results 91 to 100 of about 8,954,431 (357)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Survival of the Fixed-est: Alien Invasion of Human Identity in Octavia Butler\u27s Dawn [PDF]
, 2018 While many definitions for science fiction have been offered over the years since the genre’s inception, Robert A. Heinlein’s definition, with its easy-to-follow five-point format, remains one of the most specific and comprehensive. Heinlein argues that,
Pretzer, Jennifer
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Contemporary Social Sciences, 2017 It is generally accepted that the human mind and cognition can be viewed at five levels; nerves, psychology, language, thinking and culture. Artificial intelligence(AI) simulates human intelligence at all five levels of human cognition, however, AI has ...
Cai Shushan, Xue Xiaodi
doaj +1 more source
Experiencing Science, An Introduction to Real Methods of Science for the Preservice Teacher [PDF]
, 1999 The scientific method presented in the middle school classroom introduces the experimental approach of science in a way that may actually bear little resemblance to the processes actually used by working scientists.
Hagan, D. B., Neely-Fisher, D. L.
core +1 more source
Fictional scenarios, real concerns: science fiction and perceptions of human genome editing [PDF]
, 2023 April A. Eichmeier +4 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The human of the science. Editorial
Papeles, 2013 In this edition of the magazine Papeles we encounter two topics greatly linked to oneother: first, a debate centred on science, its constitutive exactitude and the teachingof it in universities; in particular, the contemporary debate regarding the ...
Enrique Ferrer-Corredor
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source