Results 91 to 100 of about 38,094,648 (298)
Science, Technology and Human Values
, 2016 Informational booklet about the Science, Technology and Human Values grants, administered by the Division of Special ...
National Endowment for the Humanities, Division of Research Programs
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InSpire Newsletter for 2014 [PDF]
, 2014 The 2014 issue of InSpire, a periodical focused on and produced by the College of Human Science and ...
URI College of Human Science and Services
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2005 Our society keeps growing with a large number of complicated machines and systems, while we are spending our diverse lives. The number of aged people has been increasing in the society.
Arai, Tatsuo. +6 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The sympathetic nervous system response to a Continuous Performance Task
microPublication BiologyA Continuous Performance Task is an example of a mental stressor which requires vigilance, attention, and effort. We hypothesized that a sympathetic nervous system response would be evident from a resting baseline period to this attention test, and ...
Brandon R. Bautista +5 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The human of the science. Editorial
Papeles, 2013 In this edition of the magazine Papeles we encounter two topics greatly linked to oneother: first, a debate centred on science, its constitutive exactitude and the teachingof it in universities; in particular, the contemporary debate regarding the ...
Enrique Ferrer-Corredor
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source