Results 1 to 10 of about 45,311 (311)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Exploring the Complex Effects and Their Spatial Associations of the Built Environment on the Vitality of Community Life Circles Using an eXtreme Gradient Boosting–SHapley Additive exPlanations Approach: A Case Study of Xi’an

Buildings
Disentangling the effects of the built environment on urban vitality at the scale of community life circles is crucial for informing precise urban planning and design, particularly in the context of urban renewal.
Keju Liu, Dian Zhou, Yingtao Qi, Mingzhi Zhang, Yulin Ren, Yupeng Wei, Jinghan Wang   +6 more
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

Developing a Holistic Approach for Constructing Rural Living Circles in the Loess Plateau—Taking Yongning Village as an Example

Buildings
Insufficient public service facilities in rural areas, which leads to failures in meeting the needs of villagers, has become a significant barrier to the high-quality development of rural regions.
Mengying Wang, Mingzhi Zhang, Yingtao Qi, Dingqing Zhang, Chenguang Wang, Wenying Yao, Dian Zhou   +6 more
doaj   +1 more source

Review of Culture in Maintenance Management of Public Buildings in Developing Countries

Buildings, 2022
Studies have shown that culture is one of the significant elements that influence the behavior of doing things the right way, without which there is a hindrance to the attainment of set goals.
Babatunde Fatai Ogunbayo, Clinton Ohis Aigbavboa, Wellington Thwala, Opeoluwa Akinradewo, Matthew Ikuabe, Samuel Adeniyi Adekunle   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Foliar Application of Strontium for the Identification of Roots from Specific Wheat Plants

Agriculture
In the field of crop research, the study of roots involves many challenges, particularly the lack of effective methods for identifying crop roots. To deal with this problem, this study proposes a solution strategy: in applying strontium to crop leaves ...
Senlin Fu, Di Liu, Yanjiao Tian, Xiaofeng Xu, Zhaoyong Shi   +4 more
doaj   +1 more source

Dispatching optimization of city gas station district energy systems with multiple uncertainties based on an improved affine arithmetic method

Energy Reports, 2023
According to the energy consumption characteristics of gas stations, the district energy system (DES) based on natural gas and renewable energy is a suitable form of energy supply.
Tianjie Liu, Wenling Jiao, Xinghao Tian, Xin Zhang   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source