Results 101 to 110 of about 8,852,242 (348)

Using Classified and Unclassified Land Cover Data to Estimate the Footprint of Human Settlement

Data Science Journal, 2018
Accurate, up-to-date maps of and georeferenced data about human population distribution are essential for meeting the United Nations Sustainable Development Goals progress measures, for supporting real-time crisis mapping and response efforts, and for ...
Charlie Frye, E. Nordstrand, D. Wright, Carmelle Terborgh, Jeanne Foust   +4 more
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

AI-Driven Multi-Model Classification of Rural Settlements for Targeted Rural Revitalization: A Case Study of Gaoqing County, Shandong Province, China

Land
Rural settlements are the fundamental socio-economic units of China’s countryside. In line with national strategies that emphasize place-based and category-specific pathways for rural revitalization, accurate classification of rural settlements is ...
Jing He, Xinlei Wang, Yingtao Qi, Jinghan Jiang, Dian Zhou, Ding Ma, Jing Ying   +6 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

The Implications of the Spatial Distribution of Informal Motorcycle Parking Stations in Ubungo Municipality: A Comparative Analysis of Planned and Unplanned Neighborhoods

African Journal on Land Policy and Geospatial Sciences
Context and background: The emergence of motorcycle public transportation in Dar es Salaam city has raised concerns about motorcycle parking spaces, which are safer and more convenient.
Paulo Kitosi
doaj   +1 more source

A Human Settlement Composite Index (HSCI) Derived from Nighttime Luminosity Associated with Imperviousness and Vegetation Indexes

Remote Sensing, 2018
Satellite-derived nighttime light data have been increasingly used for studying urbanization and socioeconomic dynamics, because there are notable quantitative relationships between anthropogenic nocturnal radiance and the degree of human activity over ...
Ting Ma, Tao Xu, Lin Huang, Alicia Zhou
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The paradox of enhancing male involvement in family planning uptake in rural Tanzania: insights from Bahi District, Dodoma Region

BMC Health Services Research
Background Family Planning (FP) is a requirement of global and national legal instruments to ensure its full provision to both men and women. Male involvement in FP is internationally streamlined to ensure it is achieved in resource-constrained countries.
Fabiola H. Odira, Chakupewa J. Mpambije, Yohannes E. Kachenje   +2 more
doaj   +1 more source

Vitality-Oriented Commercial Street Design Strategies: A Multi-Dimensional Quantitative Analysis of Chunxi Road, Chengdu, China

Buildings
Research efforts to explain urban vitality encompass accessibility studies, place-based qualitative studies, morphological analysis, and land use studies.
Wei Yan, Yupeng Wang, Kexin Feng
doaj   +1 more source