Results 111 to 120 of about 8,852,242 (348)

Understanding Spatiotemporal Development of Human Settlement in Hurricane-prone Areas on U.S. Atlantic and Gulf Coasts using Nighttime Remote Sensing

, 2019
. Hurricanes, as one of the most devastating natural disasters, have posed great threats to people in coastal areas. A better understanding of spatiotemporal dynamics of human settlement in hurricane-prone areas is demanded for sustainable development ...
Xiao Huang, Cuizhen Wang, Junyu Lu
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Men’s participation in maternal and child health care in Western Uganda: perspectives from the community

BMC Public Health, 2019
Background Participation of men in Maternal and Child Health (MCH) is crucial for the reduction of infant and maternal mortality. Men may be influential in making health care decisions that may affect their female partner’s access to health care services,
Florence Muheirwe, Said Nuhu
doaj   +1 more source

Simulating the development of resilient human settlement in Changsha

Journal of Geographical Science, 2022
Lisha Tang, H. Long
semanticscholar   +1 more source

Comparison of built‐up area maps produced within the global human settlement framework

Trans. GIS, 2018
The validation of built‐up areas derived from different sensors is crucial for gaining a deeper understanding of the consistency and interoperability between them.
F. Sabo, C. Corbane, A. Florczyk, S. Ferri, M. Pesaresi, T. Kemper   +5 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Oberlander, Peter. Land: The Central Human Settlement [PDF]

, 1987
Joy Woolfrey
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

ACCESS TO LAND BY FOREIGN INVESTORS IN TANZANIA

African Journal on Land Policy and Geospatial Sciences
Context and background Availability and accessibility of suitable land are crucial factors for attracting and sustaining land-based investment. Access to land has become a significant concern across various regions and countries in the 21st century ...
JOHANITHA BLANDES, UPENDO MATOTOLA
doaj   +1 more source