Results 121 to 130 of about 45,311 (311)

Herring gull aversion to gaze in urban and rural human settlements

open access: green, 2020
Madeleine Goumas   +4 more
openalex   +2 more sources

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

open access: yesAdvanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang   +16 more
wiley   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

The effects of indoor acoustic and visual environments on the mental health of older adults: a systematic review

open access: yesHumanities & Social Sciences Communications
This systematic review aims to comprehensively assess the impact of indoor audiovisual environments on the mental health of older adults and provide recommendations for future research.
Jingyi Mu   +4 more
doaj   +1 more source

Changes in the large carnivore community structure of the Judean Desert in connection to Holocene human settlement dynamics. [PDF]

open access: yesSci Rep, 2021
Lazagabaster IA   +6 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

open access: yesAdvanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram   +5 more
wiley   +1 more source

First modern human settlement recorded in the Iberian hinterland occurred during Heinrich Stadial 2 within harsh environmental conditions. [PDF]

open access: yesSci Rep, 2021
Alcaraz-Castaño M   +13 more
europepmc   +1 more source

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