Differentiation Governance of Rural Human Settlement Environments in China: Knowledge Mapping and Visualization. [PDF]
Int J Environ Res Public Health, 2023 Dai X, Zhang J, Sun X, Li J, Liu B.
europepmc +1 more source
Transition factors analysis of human settlement [PDF]
, 2010 Shih‐Yun Kuo, Ch.-J. Chen
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
BuildingsThe South African preferential procurement policy emerged from the demand for transparency, fair competition, value-for-money, standardised and benchmark pricing, and regulation of public procurement arrangements in the construction industry.
Lebogang Joseph Tau +2 more
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Spatial spillover and threshold effect of green development efficiency on urban human settlement resilience in Yangtze River Delta urban agglomeration. [PDF]
PLoS One, 2023 Wang Z, Xu X, Zhang J.
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
The Effect of Human Settlement Pedestrian Environment on Gait of Older People: An Umbrella Review. [PDF]
Int J Environ Res Public Health, 2023 Xuan C, Zhang B, Jia X.
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Comprehensive evaluation of community human settlement resilience and spatial characteristics based on the supply-demand mismatch between health activities and environment: a case study of downtown Shanghai, China. [PDF]
Global Health, 2023 Zhong Q, Chen Y, Yan J.
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