Results 41 to 50 of about 45,311 (311)

From Traditional Settlements to Arrival Cities: A Study on Contemporary Residential Patterns in Chinese Siheyuan

Buildings
With the rapid expansion of Chinese cities, traditional siheyuan in some old urban areas and historic districts have gradually transformed into overcrowded courtyard tenements inhabited primarily by rural migrants.
Mengying Wang, Xin Xu, Yingtao Qi, Dingqing Zhang   +3 more
doaj   +1 more source

HSC-GPT: A Large Language Model for Human Settlements Construction [PDF]

, 2023
Ran Chen, Yao Xueqi, Jiang Xuhui, Han Zhengqi, Guo Jing-ze, Xianyue Zhang, Lin Chunyu, Liu Chumin, Jing Zhao, Lian Zeke, Jingjing Zhang, Li Keke   +11 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Sky type classification in Harbin during winter

Journal of Asian Architecture and Building Engineering, 2020
Sky type classification is a significant element in daylight simulation. As a “winter city”, the daylight climate of Harbin is distinctive, and there is therefore a particular need to determine the most appropriate sky models to establish sky luminance ...
Ying Zi, Cheng Sun, Yunsong Han
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Development of a Mathematical Model to Size the Photovoltaic and Storage Battery Based on the Energy Demand Pattern of the House

Frontiers in Energy Research, 2022
Solar energy is used in buildings worldwide. However, because the efficiency of photovoltaic power generation varies with environmental fluctuations, it is difficult to control. Therefore, electricity generation from photovoltaics is often poorly matched
Han Chang, Feng-Lin Jing, Yao-Long Hou, Li-Qi Chen, Yi-Jun Yang, Tian-Ye Liu, Chen-Lin Wei, Bin-Qing Zhai, Cai-Ying Hou   +8 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Modelling the Impact of Blockchain Technology Barriers on Construction Procurement Systems in Nigeria

Advances in Civil Engineering
Blockchain is a decentralised system based on cryptographic procedures and smart contracts that records every transaction and shares it with all parties involved, thereby handling issues of delays and trust.
David Ojimaojo Ebiloma, Opeoluwa Akinradewo, Clinton Ohis Aigbavboa, Babatunde Fatai Ogunbayo   +3 more
doaj   +1 more source

A DELPHI TECHNIQUE APPROACH TOWARDS THE NEED FOR AND RELEVANCE OF CONSTRUCTION PROJECT MONITORING AND EVALUATION PRACTICES

Journal of Construction Project Management and Innovation, 2017
The practical experience of the researchers on the implementation of the inductive methodology to knowledge dissemination using the Delphi technique approach is reported in this study.
Callistus TENGAN, Clinton AIGVABOA
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source