Results 61 to 70 of about 8,852,242 (348)

Analysis of investment in public facilities and amenities in urban development plans in Bhutan: How systematic is it?

open access: yesWorld Development Sustainability, 2023
The Urban Development Plans (UDPs) prepared in Bhutan usually lack priority investment plans and Cost Benefit Analysis (CBA) of the proposed investments.
Bhawana Chhetri   +2 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

A Study on the Perceptual Differences in Street Space in Historic and Cultural Districts from the Host–Guest Shared Perspective: A Case Study of the Sajinqiao Area in Xi’an, China

open access: yesBuildings
In historic and cultural districts characterized by the coexistence of residential and commercial functions, street spaces play a pivotal role in shaping urban cultural continuity and local identity.
Lu Zhang   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Foliar Application of Strontium for the Identification of Roots from Specific Wheat Plants

open access: yesAgriculture
In the field of crop research, the study of roots involves many challenges, particularly the lack of effective methods for identifying crop roots. To deal with this problem, this study proposes a solution strategy: in applying strontium to crop leaves ...
Senlin Fu   +4 more
doaj   +1 more source

Review of Culture in Maintenance Management of Public Buildings in Developing Countries

open access: yesBuildings, 2022
Studies have shown that culture is one of the significant elements that influence the behavior of doing things the right way, without which there is a hindrance to the attainment of set goals.
Babatunde Fatai Ogunbayo   +5 more
doaj   +1 more source

Principles and Applications of the Global Human Settlement Layer as Baseline for the Land Use Efficiency Indicator - SDG 11.3.1

open access: yesISPRS Int. J. Geo Inf., 2018
The Global Human Settlement Layer (GHSL) produces new global spatial information, evidence-based analytics describing the human presence on the planet that is based mainly on two quantitative factors: (i) the spatial distribution (density) of built-up ...
M. Melchiorri   +4 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Modelling the Impact of Blockchain Technology Barriers on Construction Procurement Systems in Nigeria

open access: yesAdvances in Civil Engineering
Blockchain is a decentralised system based on cryptographic procedures and smart contracts that records every transaction and shares it with all parties involved, thereby handling issues of delays and trust.
David Ojimaojo Ebiloma   +3 more
doaj   +1 more source

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