Results 41 to 50 of about 271,186 (309)

Human Rights Violation Settlement by Regional Office of Ministry of Law and Human Rights In Maluku Province Through Public Communication Service

Balobe Law Journal, 2022
Introduction: Currently, there are many human rights violation allegations in Maluku either done vertically by Government or horizontally by the society. High number of complaints received by the People Communication Service (Yankomas) team in the Regional Office of Ministry of Law in Maluku and Human Rights indicates this phenomenon.
Yared Hetharie, Yosia Hetharie
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Climatic and human influences on water resources in low atolls [PDF]

, 2005
Low, small islands have water supply problems amongst the most critical in the world. Fresh groundwater, the major source of water in many atolls, is vulnerable to natural and human-induced changes.
Dray, Anne, Falkland, Tony, Metai, Eita, Metutera, Taboia, Overmars, Marc, Perez, Pascal, White, Ian M.   +6 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

For richer, for poorer: marriage and casualized sex in East African artisanal mining settlements [PDF]

, 2014
Migrants to Tanzania's artisanal gold mining sites seek mineral wealth, which is accompanied by high risks of occupational hazards, economic failure, AIDS and social censure from their home communities. Male miners in these settlements compete to attract
Bryceson D.F, Bryceson D.F., Bryceson D.F., Bujra J., Caplan P., Chachage C.S.L., Doyle S., Foucault M., Gray C., Harries P., Hodgson D.L., Kombe‐Malekela B., Moodie T.D., O'Laughlin B., Onselen C, Roberts A.D., Swantz M.L., Wilson M.   +17 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Successful, safe and sustainable cities: towards a New Urban Agenda [PDF]

, 2017
There is a growing interest among national governments and international agencies in the contribution of urban centres to sustainable development. The paper outlines the new global agendas to guide this: the Sustainable Development Goals, the Paris ...
Satterthwaite, David
core   +3 more sources

Study on the Wind Environment of the Architecture Communities: Traditional Typical Min Nan Human Settlements’ Case [PDF]

Mathematical Problems in Engineering, 2013
In contrast to the modern urban planning, which can be done in short period in terms of the spatial qualified design, the traditional tribe needs longer period in terms of the villagers’ sense of community. The selection of location, planning, and construction reveals the wisdom of the former people’s use of the resourceful life experience.
Yuan Miao, Shang-Chia Chiou
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source