Results 101 to 110 of about 8,819,593 (390)
NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang+7 more
wiley +1 more source
The issue of human sexuality has many negative implications in African society. These arose in a number of contexts – legal, religious, cultural and societal – and were significantly divisive.
Graham A. Duncan
doaj +1 more source
Amitriptyline and Sexual Function: A Systematic Review Updated for Sexual Health Practice
Amitriptyline is an old drug but is still prevalently used as the first-line treatment for a variety of common diseases. Surprisingly, knowledge of sexual risks with amitriptyline comes from only one clinical trial and several case reports from three ...
Louis Wei-Hsi Chen MD, MSc, LLM+7 more
doaj +1 more source
Can research on entactogens contribute to a deeper understanding of human sexuality? [PDF]
Holka-Pokorska J.
europepmc +1 more source
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat+8 more
wiley +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao+10 more
wiley +1 more source
Can Sexuality Education Advance Gender Equality and Strengthen Education Overall? Learning from Nigeria's Family Life and HIV Education Program [PDF]
The imperative to prepare the largest generation of young people in history for adulthood has driven a search for fresh approaches to educating adolescents about their bodies and sexuality.
Deborah Rogow, Susan Y. Wood
core
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski+13 more
wiley +1 more source
Ethical beginnings: Reflexive questioning in designing child sexuality research [PDF]
Counselling young children referred for sexualised behaviour can challenge therapists’ ideas about childhood and sexuality. This area of practice is complex and sensitive, and calls upon collaboration with a range of significant adults in children's ...
Flanagan, Paul G.
core +2 more sources
The article explores how Geoffrey Chaucer’s Canterbury Tales discusses human sexuality as a major thematic concern in both its normative and its performative dimension, and sex, an (in)tractable issue throughout the Middle Ages, as a core motif that ...
Popescu Dan Nicolae
doaj +1 more source