Results 111 to 120 of about 8,819,593 (390)

Single‐Cell RNA Seq in Sydenham Chorea Shows B Cell HLA‐DR/DQ Upregulation and Plasma Cell Proteasomal Activation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han   +9 more
wiley   +1 more source

Is There A Post-Human Sexuality? [PDF]

open access: yesJournal of Philosophical Investigations
Will human sexuality survive the passage to Artificial Intelligence? To answer this question properly, we should first analyze the paradoxical inner structure of sexuality itself, which is never simply binary: it always involves a third element that ...
Slavoj Žižek
doaj   +1 more source

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague   +8 more
wiley   +1 more source

The Social Construction of Sexuality in Primary School Classrooms [PDF]

open access: yes, 2014
Through qualitative interviews with primary school teachers, this research sought to uncover how heterosexual privilege is maintained in talk about sexuality.
Spengen, Anna
core   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim   +6 more
wiley   +1 more source

Behavioral economics-based incentives supported by mobile technology on HIV knowledge and testing frequency among Latino/a men who have sex with men and transgender women: Protocol for a randomized pilot study to test intervention feasibility and acceptability

open access: yesTrials, 2018
Background Mobile Technology and Incentives (MOTIVES) is a randomized pilot study of a mobile technology-based and behavioral economics-supported HIV prevention intervention.
Sebastian Linnemayr   +5 more
doaj   +1 more source

Long COVID in People With Multiple Sclerosis and Related Disorders: A Multicenter Cross‐Sectional Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Managing long COVID in people with multiple sclerosis and related disorders (pwMSRD) is complex due to overlapping symptoms. To address evidence gaps, we evaluated long COVID susceptibility in pwMSRD versus controls and its associations with multi‐domain function and disability.
Chen Hu   +15 more
wiley   +1 more source

Loving union and procreation: the essential significations of the conjugal act. A moral-theological reflection in occasion of the jubilee year of „Humane vitae”

open access: yesSeminare, 2020
Following the jubilee year 2018 of Pope Paul VI’s encyclical Humanae vitae (1968), the invitation of Pope Francis in Amoris laetitia should be accepted to rediscover the message of Humanae vitae.
Josef Spindelböck
doaj  

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